January 25, 2011
Seroprevalence Of Anti-HAV Among Patients With Chronic Viral Liver Disease
Hepatitis A virus (HAV) is an epidemiologically important virus with a worldwide distribution and causes acute hepatitis in humans. Acute HAV superinfection causes severe liver disease, acute liver failure and even higher mortality rates in patients with underlying chronic liver disease (CLD). Numerous studies have identified CLD as a risk factor for fulminant hepatitis and death from acute HAV infection.
A research article to be published on January 14, 2011 in the World Journal of Gastroenterology addresses this question. In this study, the authors investigated the current seroprevalence of HAV antibodies (anti-HAV) in patients with chronic viral liver disease in South Korea. They also tried to determine the age-specific seroprevalence in these patients to assess whether vaccination against HAV is necessary in all patients who have underlying viral liver diseases, and to determine the factors that affect IgG anti-HAV seropositivity.
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