February 2, 2011
New Gift From Mother Nature’s Medicine Chest May Help Prevent And Treat Bone Diseases
One of Mother Nature's latest gifts to medical science is stirring excitement with the discovery that the substance "” obtained from a coral-reef inhabiting cyanobacterium "” appears to be an ideal blueprint for developing new drugs for serious fractures, osteoporosis, and other bone diseases. That's the conclusion of a study on the substance, Largazole, in the journal ACS Medicinal Chemistry Letters.
By some estimates, more than half of today's medications are in Largazole's family, the "natural products." They come from trees, snails, scorpion venom, soil bacteria, other plants and animals; however, so far only a few come from the ocean. In the report, Jiyong Hong, Seong Hwan Kim, Hendrik Luesch and colleagues indicate that Largazole was derived from and named for marine cyanobacteria that grow in Key Largo, Florida. Largazole, they add, already has attracted scientific attention for its ability to kill cancer cells in laboratory experiments.
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