February 4, 2011

Reduced Lung Deficiency Linked To Vitamin D Deficiency

(Ivanhoe Newswire) -- New research shows vitamin D deficiency is widespread among patients with interstitial lung disease (ILD), with the most prevalent seen in patients with concurrent connective tissue disease (CTD).

Researchers from the University of Cincinnati College of Medicine assessed vitamin D levels in 67 patients with CTD-ILD in addition to 51 patients with other forms of ILD.  Results showed the overall incidence of vitamin D deficiency and insufficiency was 38 percent and 59 percent, in that order.

Those with CTD-ILD were far more likely to have vitamin D deficiency (52 percent vs. 20 percent) and insufficiency (79 percent vs. 31 percent) than other forms of ILD.  Among patients with CTD-ILD, reduced vitamin D levels were strongly associated with reduced lung function.  Researchers conclude that vitamin D might have a role in the pathogenesis of CTD-ILD.

SOURCE: Chest, 1 February 2011