February 14, 2011

Magnesium Protects Against CP?

(Ivanhoe Newswire) -- Something as simple as magnesium may protect against cerebral palsy (CP). A new study in mice shows consuming magnesium sulfate significantly reduces brain injury associated with maternal inflammation or infection.

Magnesium sulfate is sometimes used during preterm labor to reduce the risk of neonatal brain injury. In 2010, the American College of Obstetricians and Gynecologists along with the Society for Maternal-Fetal Medicine issued a statement saying that "available evidence suggests that magnesium sulfate given before anticipated preterm birth reduces the risk of cerebral palsy in surviving infants."

"We knew there were indications from other studies that magnesium sulfate might protect a preterm fetus from cerebral palsy, but we wanted to demonstrate direct and conclusive protective effect on the offspring brain in cases of maternal inflammation," Ron Beloosesky, M.D., one of the study's authors, was quoted as saying. "We wanted to learn more about the protective effects of Mg in cases where maternal inflammation causes preterm birth, so we used the very sensitive diffusion tensor imaging, Magnetic Resonance Imaging to study how Mg works."

Results of the study showed that magnesium sulfate treatment significantly reduced the risk of neonatal brain injury associated with maternal LPS. Beloosesky said the next step is to conduct more studies to understand how magnesium sulfate works and protects the fetal brain.

SOURCE: The Society for Maternal-Fetal Medicine's annual meeting in San Francisco, Feb. 10, 2011