March 16, 2011
Inside Look At How Elite Control HIV
(Ivanhoe Newswire) -- In the years since the AIDS epidemic began, it has become clear that there is substantial variation in the way that individuals respond to HIV infection. Although most progress quickly from initial infection to immunodeficiency, a small subset survive for long periods without developing symptoms.
These patients, dubbed elite controllers, display undetectable levels of viral replication, but the mechanism that explains how their immune systems effectively control the virus is not understood.
The researchers hope that this finding may inform the design and development of treatment strategies for patients who are more susceptible to the virus' tragic effects.
SOURCE: Journal of Clinical Investigation, published online March 14, 2011