April 29, 2011
Prevent Cervical Cancer: A Working Strategy?
(Ivanhoe Newswire) --A long-term surveillance strategy for women treated for precancerous cervical lesions may be helping to prevent cervical cancer.
A new study confirmed that the currently used post-treatment approach (three cytological smears) is effective for identifying women at long-term risk of cervical cancer. Researchers say this is important because about 15 percent of women diagnosed with high-grade cervical intraepithelial neoplasia (CIN) will develop recurrent disease, even if they undergo treatment.
Researchers found that the five-year risk of developing post-treatment CIN 2 or higher was 16.5 percent. However, that risk was reduced to less than 3 percent in women who had three consecutive cytological normal smears.
Findings also showed that by adding hrHPV testing to post-treatment surveillance, testing
at 12 months could be omitted in women who are negative by co-testing at six months.
"The five-year risks of post-treatment disease in these women are such that they do not need to be followed up more closely than women in population-based screening (every five years)"¦and could therefore return to [regular screening]," the authors were quoted as saying.
The authors concluded by saying that more intensive surveillance is critical for women at a higher risk of recurrence.
Source: Lancet Oncology, April 27, 2011