Fragrance Ingredients Evaluated by RIFM Group Approach Shown to be Safe
WOODCLIFF LAKE, N.J., June 1, 2011 /PRNewswire-USNewswire/ — RIFM’s latest group summary, A Safety Assessment of Saturated Branched Chain Alcohols when used as Fragrance Ingredients, published in Food and Chemical Toxicology, Vol. 48, Supplement 4, July 2010 is now available from the Research Institute for Fragrance Materials, Inc. (RIFM) web site at http://www.rifm.org/publications-details.php?id=25. Paper copies are available by e-mailing firstname.lastname@example.org.
The group summary on Saturated Branched Chain Alcohols and its related Fragrance Material Reviews (FMRs) consists of 20 materials: 12 primary, 5 secondary and 3 tertiary alcohols. These alcohols share common structural elements and are used in decorative cosmetics, fine fragrances, shampoos, and toilet soaps as well in non-cosmetic products such as household cleaners and detergents. The Expert Panel is of the opinion that there are no safety concerns regarding these fragrance ingredients under the current declared levels of use.
The group assessment approach based on structural relationship, enabling consistency in predicting metabolism and toxicity, conserves resources by reducing duplicate testing. The group summary publications and related FMRs provide the scientific and regulatory communities with all the toxicological data available to RIFM on these fragrance ingredients. This includes RIFM sponsored studies, company sponsored studies and data that appear in the peer-reviewed literature. They provide the Expert Panel’s safety assessment of these groups and support the structure of RIFM’s safety assurance program. They are also used by industry to meet REACH requirements. Dr. Anne Marie Api, RIFM Vice President, Human Health Science, said, “The Group Summary approach is part of our proactive program. We now have 10 group summaries and more than 200 FMRs published.” There are plans to publish group summaries on Macrocyclic Ketones, Macrocyclic Lactones and Lactides, Aryl Alkyl Alcohols and Aryl Alkyl Alcohol Simple Acid Esters.
RIFM is the international scientific authority for the safe use of fragrance materials. RIFM generates, evaluates and distributes scientific data on the safety assessment of fragrance raw materials found in personal and household care products. Through extensive research, testing and constant monitoring of all scientific literature available, RIFM maintains its Database as the most comprehensive source worldwide of physical-chemical, toxicological and eco-toxicological data associated with known fragrance and flavor materials. All of RIFM’s scientific findings are evaluated by an independent Expert Panel–an international group of dermatologists, pathologists, toxicologists, respiratory, reproductive and environmental scientists. The Expert Panel evaluates the safety of fragrance ingredients under conditions of intended use and publishes its results in peer-reviewed scientific journals. The decisions of the Expert Panel regarding restrictions of use are also published as IFRA Standards, publicly available from the International Fragrance Association (IFRA) web site at www.ifraorg.org. For more information about RIFM and its activities, visit www.rifm.org or e-mail email@example.com.
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SOURCE Research Institute for Fragrance Materials, Inc.