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Drugs equivalent in angina treatment: study

Posted on: Tuesday, 22 November 2005, 16:13 CST

CHICAGO (Reuters) - The blood-thinning drug Lovenox works as well as a standard artery-clearing drug in patients with severe heart-related chest pain, but neither reduced the risk of death after a year of treatment, a study said on Tuesday.

The research, paid for by Aventis Pharmaceuticals, a member of the Sanofi-Aventis Group which makes Lovenox, involved nearly 10,000 patients at 487 hospitals in 12 countries who suffered from acute coronary syndromes -- severe angina that cannot be treated with surgery or angioplasty.

They had undergone revascularization, a treatment in which small holes are laser-drilled in the heart tissue to improve blood flow.

In the study, which covered a year, the patients were treated with either enoxaparin, the generic name for Lovenox, or a form of heparin, the standard medicine used in many hospitals for artery-clearing.

After one year the death rates in the two treatment groups were similar, said the report from the Duke Clinical Research Institute, in Durham, North Carolina.

"High-risk patients with acute coronary syndromes remain susceptible to continued cardiac events despite aggressive therapies," concluded the report published in this week's Journal of the American Medical Association.


Source: REUTERS

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