Deputy Director of Cold Spring Harbor Laboratory Cancer Center Wins Research Prize
Posted on: Friday, 2 December 2005, 21:00 CST
By Henry E. Powderly II
Scott W. Lowe's job is no small task. He is deputy director of the Cold Spring Harbor Laboratory Cancer Center and a Howard Hughes Medical Institute investigator. His work has not gone unrecognized. This month, Lowe won the 2005 Paul Marks Prize for Cancer Research.
The Paul Marks Prize is granted by the Memorial Sloan-Kettering Cancer Center.
Lowe explores the molecular workings of apoptosis and senescence in health cells. Apoptisis is what programs a cell to die. Senescence occurs when cells stop dividing yet remain alive. Both of these activities are disrupted in cancerous cells, which is why tumors grow. Lowe studies the gene that contributes to tumor growth.
Lowe also has developed new models for studying cancer in mice.
These models have allowed us to understand the evolution of cancer, how it progresses and responds to therapy, he said. He uses the mice to study how apoptisis and senescence can be restored, allowing traditional chemotherapy to destroy the tumor. He's also trying to gain insight into genetic factors that determine if cancer therapies will be effective.
Our long term goal is to use these models to determine how to make chemotherapy agents that are more effective, he said.
Lowe will receive his award at the Memorial Sloan-Kettering Cancer Center on Dec. 1.
Source: Long Island Business News
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