Improved Cancer Therapy Researched
Posted on: Wednesday, 22 February 2006, 18:00 CST
Scripps Research Institute scientists in La Jolla, Calif., say they have discovered antibody-interleukin complexes stimulate immune responses.
The researchers found injections of a certain cytokine, together with the right monoclonal antibody, increases white blood cells that coordinate immune responses to tumor and infected cells.
The scientists say their discovery might lead to an improved cancer therapy that helps patients boost their own immune response to the disease.
The findings might also be significant for developing new ways to help patients with autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, or juvenile diabetes.
The study showed the injections caused a massive selective increase in the immune system's two main types of T cells. Our study shows that different cytokine-antibody complexes such as IL-2/IL-2 mAb could be clinically useful to selectively boost or inhibit the immune response in vivo, said Onur Boyman, a member of the Scripps Research Department of Immunology and lead author of the study.
The research is reported in the Feb. 16 issue of the online journal Science Express.
Source: United Press International
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