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Is There a Link Between Obesity, Diabetes, Erectile Dysfunction and Cardiovascular Disease?

Posted on: Friday, 3 March 2006, 06:00 CST

By Anonymous

214

IS THERE A LINK BETWEEN OBESITY; DIABETES, ERECTILE DYSFUNCTION AND CARDIOVASCULAR DISEASE?

K.S. Charnier1,2

1 Sheffield Hallam University, Sheffield, United Kingdom; 2 Royal Hallamshire Hospital, Sheffield, United Kingdom

Mortality from coronary heart disease increases with age and is at least twice as prevalent in men compared with agematched women. Female sex hormones were thought to be protective but two large randomised controlled trials have produced negative results for cardiovascular health preservation. What is it about men? There is a natural change in male body shape with age in association with falling testosterone blood levels. Elderly men develop fat redistribution to the trunkal area. Is this itself an adverse cardiac risk factor? Age is also independently associated with worsening insulin resistance which is a recognised cardiac risk factor. How do trunkal obesity, increasing insulin resistance and falling testosterone levels combine to affect cardiovascular risk? Does male hormone replacement therapy reverse any of this adverse risk profile? In this presentation I will try to answer these important questions by reference to published studies.

Copyright CRC Press Mar 2006


Source: Aging Male

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