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Last updated on February 13, 2012 at 17:08 EST

Thomson Scientific Names ‘Red-Hot’ Research Papers of 2005

March 20, 2006

PHILADELPHIA and LONDON, March 20 /PRNewswire-FirstCall/ — The New England Journal of Medicine leads the pack in this year’s “Red-Hot Research Papers” rankings by publishing the most-cited research paper of 2005. This, according to the March/April issue of Science Watch – the bimonthly newsletter published by Thomson Scientific, a business unit of The Thomson Corporation.

New England Journal of Medicine (NEJM) boasts this ranking in a year that seems to have been dominated by highly cited articles in medical publications. Thirteen of the top-40 most-cited papers were published in NEJM, with four of the top-five most-cited articles appearing in its pages.

The research group led by Paul M. Ridker, Harvard University professor of medicine, tops the list of Red-Hot Research Papers for “C-reactive protein levels and outcomes after statin therapy,” published in NEJM, January 2005. Ridker is also the only researcher to be listed as the first author on more than one paper – numbers one and 30.

“Our annual roundup of the hottest research papers celebrates researchers whose work influences modern scientific thought,” said Christopher King, editor of Science Watch. “It also helps us spot trends and ‘hot’ fields of study. This year, for example, we see that many of the ‘hottest’ papers were published in medical publications.”

                    The Red-Hot Research Papers of 2005                   (Ordered by total citations per paper)    Rank  Name          Paper                        Journal        Citations     1    P.M. Ridker,  “C-reactive protein          New England       124         et al.        levels and outcomes after    Journal of Med.                       statin therapy”     2    G.H. Bardy,   “Amiodarone or an            New England       107         et al.        implantable cardioverter-    Journal of Med.                       defibrillator for                       congestive heart failure”     3    S.D. Solomon, “Cardiovascular risk         New England        97         et al.        associated with celecoxib    Journal of Med.                       in a clinical trial for                       colorectal adenoma                       prevention”     4    R.S.          “Cardiovascular events       New England        93         Bresalier,    associated with rofecoxib    Journal of Med.         et al.        in a colorectal adenoma                       chemoprevention trial”     5    J.C. Barrett, “Haploview: analysis and     Bioinformatics     90         et al.        visualization of LD and                       haplotype maps”     6    S.E. Nissen,  “Statin therapy, LDL         New England        82         et al.        cholesterol, C-reactive      Journal of Med.                       protein, and coronary                       artery disease”     7    D.A. Hinds,   “Whole-genome patterns       Science            74         et al.        of common DNA variation                       in three human populations”     8    L.P. Lim,     “Microarray analysis shows   Nature             73         et al.        that some microRNAs                       downregulate large numbers                       of target mRNAs”     9    E.R. Miller,  “Meta-analysis: High         Annals of          73         et al.        dosage vitamin E             Internal                       supplementation may          Medicine                       increase all-cause                       mortality”     10   A. Howell,    “Results of the ATAC         Lancet             69         et al.        (Arimidex, Tamoxifen, Alone                       or in Combination) trial                       after completion of 5 years’                       adjuvant treatment for                       breast cancer”

By far, the field of medicine received the most attention in 2005, with 21 of the top-40 “Hottest Papers” appearing in medicine-focused publications. The two publications that appear most frequently on the list, NEJM and the Lancet, both fall into this category. Multidisciplinary publications (including Science and Nature, which appear third and fourth on the list, respectively), accounted for 10 of the papers included in the rankings.

                        Journal subject categories:        (Ordered by number of Red-Hot Research Papers in the field)                                          Number of    Subject category                     “Red-Hot”                                           Papers     Medicine                                 21    Multidisciplinary                        10    Biochemistry & Molecular Biology          4    Physics                                   2    Astronomy                                 1    Computer Science                          1    Oncology                                  1                                   Journals:  (Ordered by number of Red-Hot Research Papers published in the journal)                                          Number of    Publication                          “Red-Hot”                                           Papers     New England Journal of Medicine          13    Lancet                                    6    Science                                   5    Nature                                    4    Nucleic Acids Research                    3    Physics Review Letter                     2    Annals of Internal Medicine               1    Astronomy Journal                         1    Bioinformatics                            1    Cancer Cell                               1    Cell                                      1    Journal of the Natn’l Cancer Institute    1    Nature Materials                          1    

The Science Watch rankings are part of the publication’s annual rankings of the hottest researchers and papers of the year. For the rankings, Thomson Scientific evaluated the number of citations each paper received as indexed in its Web of Science(R) database (as of late December 2005). All of the papers listed in the rankings were published in 2005.

To learn about Science Watch’s “Hottest Researchers of 2004-2005″ or for more information about the hottest research papers, contact Rodney Yancey at 215-823-5397 or rodney.yancey@thomson.com.

About The Thomson Corporation

The Thomson Corporation (http://www.thomson.com/), with 2005 revenues of $8.7 billion, is a global leader in providing integrated information solutions to business and professional customers. Thomson provides value-added information, software tools and applications to more than 20 million users in the fields of law, tax, accounting, financial services, higher education, reference information, corporate e-learning and assessment, scientific research and healthcare. With operational headquarters in Stamford, Conn., Thomson has approximately 40,000 employees and provides services in approximately 130 countries. The Corporation’s common shares are listed on the New York and Toronto stock exchanges Toronto.

Thomson Scientific is a business of The Thomson Corporation. Its information solutions assist professionals at every stage of research and development – from discovery to analysis to product development and distribution. Thomson scientific information solutions can be found at http://www.scientific.thomson.com/.

NOTE: For information on subscribing to Science Watch, contact Rodney Yancey at 215-386-6362 or by email at Rodney.yancey@thomson.com.

Thomson Scientific

CONTACT: Rodney Yancey, Manager, Corporate Communications, ThomsonScientific, +1-215-823-5397, rodney.yancey@thomson.com; or Chris Lukach, AnneKlein & Associates, +1-856-988-6560 extension 15, chris@mail.akleinpr.com, forThomson Scientific

Web site: http://www.scientific.thomson.com/http://www.thomson.com/