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Research Studies HRT, Breast Cancer Risks

Posted on: Thursday, 23 March 2006, 15:00 CST

A British study of data on 1 million women says hormone replacement therapy raises the risks of some types of breast cancer but not of others.

The findings, presented at the Fifth European Breast Cancer Conference in Nice, France, found women who took HRT had an increased risk of developing lobular cancer, affecting the cells in the ducts of the milk-producing glands, and tubular cancer, a rare form of ductal cancer so-named because of the shape of the cells.

But there was not such an increased risk of developing the most common form of ductal breast cancer, the study said.

There was also no increase in the risk of medullary breast cancer, common in women with a genetic predisposition.

The study said women who had taken combined HRT (estrogen and progesterone) had an even greater risk of developing lobular and tubular breast cancer than women on estrogen only HRT.

One possible explanation for the findings is that certain types of breast cancer are more likely than others to be hormone receptive, said one of the researchers.

Further research into this topic could greatly help our understanding of the biological mechanisms underlying the development of breast cancer.


Source: United Press International

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