Test May Help Predict Renal Disease
Posted on: Thursday, 13 April 2006, 12:00 CDT
Routine blood and urine tests may help to predict the risk of end-stage renal disease developing later in life, a U.S. study finds.
Abnormal results on the urine dipstick test, which detects protein in urine, and a blood test to estimate kidney function can identify patients at increased risk of ESRD -- permanent loss of kidney function requiring dialysis or transplantation, according to study leader Dr. Areef Ishani of the Minneapolis Veterans Affairs Medical Center.
The researchers used data on nearly 13,000 men enrolled in a long-term study of cardiovascular disease prevention beginning in 1972-75, when the men were 35 to 57 years old.
Over 25 years, 1.7 percent of the men developed ESRD or died of kidney disease. Men who had more than a trace amount of protein in their urine in middle age were at triple the risk of ESRD at follow-up. For those with a stronger positive result, ESRD risk was more than 15 times higher than in men with a normal dipstick result.
The findings are published in the May Journal of the American Society of Nephrology.
Source: United Press International
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