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Orthovita to Present at Needham & Company, LLC, Fifth Annual Biotechnology and Medical Technology Conference

June 8, 2006
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Orthovita, Inc. (NASDAQ NM: VITA), a leading developer of orthopedic biomaterials, announced today that it will participate as a presenting company at the Needham & Company, LLC, Fifth Annual Biotechnology and Medical Technology Conference. Antony Koblish, chief executive officer of Orthovita, is scheduled to present on Wednesday, June 14th, at 2:30 p.m. Eastern Time, at the New York Palace Hotel, 455 Madison Avenue, New York, NY. A live webcast of this presentation will be available at http://www.wsw.com/webcast/needham15/vita/ and will be archived at the same URL for on-demand listening for 30 days following the conference.

About the Company

Orthovita is a biomaterials company with proprietary technologies for the development and commercialization of synthetic, biologically active, tissue engineering products for orthopedic and neurosurgical applications. Our products are used in the regeneration of bone and soft tissue healing. Our near-term commercial business is based on our internally developed VITOSS(R) Bone Graft Substitute technology platforms, which are designed to address the non-structural bone graft market by offering synthetic alternatives to the use of autograft or cadaver-derived bone material to meet a broad range of orthopedic clinical needs in the spine, trauma, joint reconstruction, revision surgery and extremities markets, and VITAGEL(TM) Surgical Hemostat, which is an adherent matrix and an impermeable barrier to blood flow. Our longer-term U.S. clinical development program is focused on our internally developed CORTOSS(R) Synthetic Cortical Bone technology platform, which is designed for injections in osteoporotic spines to treat vertebral compression fractures. Orthovita works jointly with Kensey Nash Corporation and Angiotech Pharmaceuticals, Inc., to develop and market synthetic-based biomaterial products, and continues to pursue similar relationships with other companies in biomaterials.

Cautionary Note Regarding Forward-Looking Statements

This press release may contain forward-looking statements regarding Orthovita’s current expectations of future events that involve risks and uncertainties as listed from time to time in reports we file with the U.S. Securities and Exchange Commission (SEC), including but not limited to risks described in our most recently filed Form 10-K and Form 10-Q under the caption “Certain Risks Related to Our Business”. Further information about these and other relevant risks and uncertainties may be found in Orthovita’s filings with the SEC, all of which are available from the SEC as well as from Orthovita upon request. Orthovita undertakes no obligation to publicly update any forward-looking statements.