OraQuick(R) Advance(TM) to Be Featured As Part of D.C Health Department’s City-Wide HIV Testing Campaign Launch on June 27, 2006

OraSure Technologies, Inc. (NASDAQ: OSUR):

 WHAT:   OraSure Technologies, Inc. (NASDAQ: OSUR) will take part in         the official launch of the D.C. Health Department’s city-wide         HIV testing campaign on June 27, National HIV Testing Day         (NHTD).          The citywide campaign will encourage all District residents to         learn their HIV status. The D.C. Health Department plans on         distributing tests through a variety of settings including         hospital emergency rooms, private physicians’ offices,         community health programs and public health settings.          OraSure’s OraQuick(R) ADVANCE(TM) Rapid HIV-1/2 Antibody Test         is the first and only U.S. FDA approved oral fluid rapid HIV         test that can detect antibodies to both HIV-1 and HIV-2 in 20         minutes The test can be used not only with oral fluid, but         also with finger-stick or venipuncture whole blood or plasma         specimens – offering ease of use and accessibility in a         variety of settings.          In observance of NHTD, OraSure’s CEO and President Doug         Michels will address the importance of HIV testing and         prevention at a press conference hosted by the National         Association of People With AIDS (NAPWA) on Monday, June 26.         The Company will also join with NAPWA and POZ Magazine to Open         the NASDAQ Stock Market on NHTD, as part of OraSure and         NAPWA’s Mayor’s Campaign Against HIV(TM). 

WHEN/WHERE

— National Association of People With AIDS Press Conference:

June 26th, 9-11 AM, National Press Club’s First Amendment

Room, Washington DC

— District of Columbia HIV Testing Campaign Launch Event – June

27th, 10 AM, Freedom Plaza, Washington DC

— NASDAQ Opening Bell Ceremony – June 27th, 9 AM, at NASDAQ’s

MarketSite, New York City

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