Migraine drug with antidepressants may harm: FDA

WASHINGTON (Reuters) – The use of some migraine drugs with
certain antidepressants can cause a fatal condition in which
patients experience hallucinations, overactive reflexes and
rapid heart beat, the U.S. Food and Drug Administration warned
on Wednesday.

The antidepressants of concern include selective serotonin
reuptake inhibitors and selective serotonin/norepinephrine
reuptake inhibitors, the FDA said.

Patients should talk to their doctors before discontinuing
antidepressant or migraine drugs known as triptans, it added.