PSA: Signaling When Cancer Treatment Works
Posted on: Wednesday, 23 August 2006, 21:00 CDT
U.S. scientists say the prostate specific antigen, or PSA, level used to detect prostate cancer might also help doctors know when treatment is working.
A University of Michigan-led study showed a man's PSA level after seven months of hormone therapy for advanced prostate cancer predicted how long he would survive.
The study at the university's Comprehensive Cancer Center evaluated 1,345 men with prostate cancer that had spread to distant parts of the body. The men were treated with seven months of androgen deprivation therapy, a treatment designed to block the effects of hormones on the cancer and their PSA levels were monitored.
The researchers found men whose PSA dropped below 4.0 ng/ml had a quarter the risk of dying compared with those whose PSA was more than 4.0.
The study is detailed in the Journal of Clinical Oncology.
Source: United Press International
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