Genome Study of Prostate Cancer Announced
Posted on: Wednesday, 11 October 2006, 15:00 CDT
Researchers from 14 U.S. institutions have announced results of the first genome-wide linkage study of prostate cancer among African-Americans.
Using genetic markers, the researchers say they identified several regions of the human genome that likely contain genes that, when altered, increase the risk of developing prostate cancer.
The study was conducted by the African-American Hereditary Prostate Cancer Study Network to help determine if heredity plays a role in the disparity in prostate cancer rates seen among African-American men.
Using genetic markers, researchers said they were able to map several regions of the human genome that likely contain genes that, when mutated, predisposed the men to developing prostate cancer.
We now must sift through millions of bases of genome sequence to identify the proverbial 'needle in the haystack,' said molecular geneticist John Carpten, senior author of the study and director of the Translational Genomics Research Institute's Integrated Cancer Genomics Division in Phoenix. The discovery of these genes will hopefully lead to new and improved modes of diagnosis and treatment for some men with prostate cancer.
The study appears in the journal Prostate.
Source: United Press International
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