Single Dose of Vical Flu Vaccine Provides 100% Protection
Posted on: Monday, 23 October 2006, 12:01 CDT
Vical Incorporated has reported that a single injection of the company's lead avian influenza DNA vaccine candidate provided 100% protection in ferrets against a highly virulent H5N1 virus.
Conventional vaccines under development for avian flu typically have required two or more doses in humans. A single-dose vaccine regimen could prove beneficial during a pandemic, both in extending vaccine supply to protect a greater number of people, and in achieving protective immune responses as quickly as possible.
The company had previously demonstrated that two doses of the vaccine candidate provided 100% protection in mice and ferrets against lethal challenges with H5N1 virus.
"Our goal is to advance into human testing with this program as quickly as possible, both to provide a potential defense against a pandemic outbreak and to explore the potential for a seasonal flu vaccine using a similar approach," said Vijay Samant, president and CEO of Vical.
Financial support for the study was provided under previously-announced grants from the National Institute of Allergy and Infectious Diseases.
Source: Datamonitor
Related Articles
- NOVAVAX Announces Publication of a Preclinical Study Demonstrating that a Virus-like Particle Vaccine Provided Protection Against Highly Pathogenic H1N1 and H5N1 Influenza Strains
- EndoBiologics, Incorporated, and PATH Form New Collaboration to Research Vaccine Candidates Against Diarrheal Disease
- Medicago's H5N1 VLP Vaccine Provides Protection Against Multiple Strains of Avian Flu
- Flu Vaccine Protects Against Only 27% of Texas Cases
- Novavax Pandemic Flu Vaccine Provided Protection Against a Lethal Challenge of Live Virus, Pre-Clinical Data Show
- GSK's Vaccine Protects Against Bird Flu
- Vaccine Approved Against Cervical Cancer
- Vical's DNA Vaccine Provides Complete Protection Against Avian Influenza and Demonstrates Cross-Protection Against Multiple Human Flu Strains in Animal Studies
- Britain Plans to Vaccinate People Against Bird Flu
- Mozambique Launches Vaccination Campaign Against Measles, Polio
 |
 |
User Comments (0)
RSS Feeds