Genes Influence Blood Pressure By Gender
Posted on: Monday, 18 December 2006, 18:00 CST
A University of California-San Diego School of Medicine study showed that the influence of genes on blood pressure may vary based on gender.
Sex is like a prism that refracts the effects of the gene very differently for men and women, said Dr. Daniel T. O'Connor, whose study is online in advance of publication in the January issue of the journal Hypertension.
The research team said it found that the gene-by-sex interaction was the rule, not the exception in the study of a large, community-based sample of primary-care patients in Southern California. They set out to discover whether gender interacts with genes in contributing to extremes of blood pressure by looking at the medical records of 611 male and 656 female, aged-matched, Caucasian patients whose blood-pressure readings fell in the top and bottom 5 percent among 53,000 patients.
Knowing these genetic mutations may help us better diagnose hypertension and select the appropriate therapy, said O'Connor.
Source: United Press International
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