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Study: Rabies Vaccine Might Fight Disease

Posted on: Wednesday, 4 April 2007, 12:00 CDT

U.S. scientists have used a weakened rabies virus to vaccinate laboratory primates against an AIDS-like disease.

Researchers at Jefferson Medical College used a drastically weakened rabies virus to ferry HIV-related proteins into animals, in essence vaccinating them against an AIDS-like disease.

The study suggests rabies might hold a key to defeating the human immunodeficiency virus -- the cause of AIDS.

The scientists said two years after the initial vaccination, four vaccinated non-human primates remained protected from disease, even after being challenged with a dangerous animal-human virus. Two control animals developed an AIDS-like disease.

We still need a vaccine that protects from HIV infection but protecting against developing disease can be a very important step, said lead investigator Professor Matthias Schnell, noting researchers aren't sure how long the viral immunity will last.

The study is reported in the Journal of Infectious Diseases.


Source: United Press International

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