Behcet’s Disease

* WHAT: A rare, chronic inflammatory disorder with an unknown cause. Pronounced “BAY-sets,” it generally begins in people in their 20s or 30s, though it can happen at any age. It tends to occur more often in men.

* SYMPTOMS: Recurrent ulcers in the mouth (resembling canker sores) and on the genitals, and eye inflammation. The disorder also may cause various types of skin lesions, arthritis, bowel inflammation, meningitis and cranial nerve palsies. It may involve all organs and affect the central nervous system, causing memory loss and impaired speech, balance and movement.

* EFFECTS: May include blindness, stroke, swelling of the spinal cord and intestinal problems.

* TREATMENT: Symptomatic and supportive. Medication may be prescribed to reduce inflammation or regulate the immune system. Immunosuppressive therapy may be considered.

* PROGNOSIS: It’s a lifelong disorder that comes and goes. Permanent remission has not been reported.

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