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Treatment May Help Lung Cancer Outcomes

Posted on: Friday, 29 June 2007, 18:05 CDT

Patients with inoperable non-small cell lung cancer who get a high chemotherapy dose before treatment may have a better outcome, says a U.S. study.

Researchers at the M.D. Anderson Cancer Center in Houston wanted to test the efficacy of giving a high dose of chemotherapy before chemoradiation begins. Induction chemotherapy is when doctors administer medicine to stop the growth of the cancer in the lungs from spreading to other parts of the body.

A total of 265 patients with inoperable non-small cell lung cancer were divided into two groups; one group of 127 patients received the induction therapy and the chemoradiation, with the second group of 138 treated with chemoradiation alone.

The researchers found a small but significant increase in overall survival in the patients who received the induction therapy with chemoradiation versus the chemoradiation-only group.

Those patients who received induction therapy as part of their treatment saw an increase in overall survival by an average of six months as compared to the group who did not receive the initial dose of chemotherapy, according to the study published in the July 1 issue of the International Journal of Radiation Oncology Biology Physics.


Source: United Press International

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