December 23, 2011
Rapid Evolution In Domestic Animals Sheds Light On The Genetic Changes Underlying Evolution
A complex genomic rearrangement causes a fascinating phenotype in chickens in which a massive expansion of pigment cells not only makes the skin and comb black, but also results in black internal organs
A new study describes how a complex genomic rearrangement causes a fascinating phenotype in chickens in which a massive expansion of pigment cells not only makes the skin and comb black, but also results in black internal organs. Published in PLoS Genetics, researchers at Uppsala University, the Swedish University of Agricultural Sciences, North Carolina State University, and National Chung-Hsing University investigated the genetic basis of fibromelanosis, a breed characteristic of the Chinese Silkie chicken.
"We have shown that the genetic change causing fibromelanosis is a complex rearrangement that leads to increased expression of Endothelin 3, a gene known for promoting the growth of pigment cells," explains Ben Dorshorst, one of the authors.
The genetic changes underlying the evolution of new species are still poorly understood. For instance, we know little about critical changes that have happened during human evolution. Genetic studies in domestic animals can shed light on this process due to the rapid evolution they have undergone over the last 10,000 years.
The research group, led by Leif Andersson, has characterized a number of traits in domestic animals, and a clear trend is emerging: genomic rearrangements have contributed significantly to the rapid evolution of domestic animals.
"We have good reason to believe that such rearrangements have also played a significant role in the evolution of other species, including ourselves," concludes Leif Andersson.
On the Net: