Common Plant Kills Leukemia Stem Cells
Posted on: Thursday, 24 February 2005, 00:00 CST
Scientists at the University of Rochester, N.Y., say a plant known as Feverfew is the source of an agent that kills human leukemia stem cells.
A compound found in the daisy-plant, also known as Bachelor's Button, kills the cells as does no other single therapy, said a team from the university Medical Center's James Wilmot Cancer Center.
The team said they collaborated with University of Kentucky chemists who identified a water-soluble molecule that has the same properties as parthenolide, a main component of the plant. However, they said it will take months before a useable, pharmaceutical compound can be made from the compound.
The National Cancer Institute has accepted the discovery into its rapid access program, which aims to move experimental drugs from the laboratory to human clinical trials as quickly as possible.
This research is a very important step in setting the stage for future development of a new therapy for leukemia, said study co-lead author Craig Jordan.
The study is reported in the online edition of the medical journal Blood.
Source: United Press International
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