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Government: Chantix Most Effective at Helping Smokers Quit

Posted on: Friday, 9 May 2008, 00:00 CDT

The federal government's new advice to doctors for helping smokers quit recommends the drug Chantix, which has recently been linked with depression and suicidal behavior.

The new guidelines mention the psychiatric risks but also say the popular Pfizer Inc. drug is the most effective at helping people get off cigarettes. The guidelines mention other options, too, and highly recommend combining counseling and medication. But doctors are encouraged to talk to all smokers who want to quit about trying medication.

Consumer advocates cautioned that the safety picture on Chantix is incomplete because it's a relatively new drug, on the market just since 2006.

"It is somewhat better than other therapies; on the other hand, it appears to have more risk," said Dr. Sidney Wolfe, of the watchdog group Public Citizen. "That part of the risk-benefit equation is missing."

Another issue with the quit-smoking guidelines, released this week by the U.S. Public Health Service, is the lead author's past connections with Pfizer. Dr. Michael Fiore, an expert on smoking issues, was a consultant to the maker of Chantix. But he said he cut those ties in 2005.

The guidelines are based on an extensive review of scientific evidence, were reviewed by 90 independent experts and were endorsed by 60 public health entities, Fiore said, adding that his past financial ties to the drug industry had no influence.


Source: Telegraph - Herald

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