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Reminder – Metabolix to Conduct a Webcast of Its Third Quarter 2008 Earnings Call

November 3, 2008

Metabolix, Inc. (NASDAQ: MBLX), a bioscience company focused on developing clean, sustainable solutions for plastics, chemicals and energy, announced today that it will be releasing its third quarter 2008 financial results after the market close on Wednesday, November 5, 2008. The full text of the earnings release will also be available on the Company’s website at www.metabolix.com.

Richard Eno, the Company’s President and CEO, and Joseph Hill, CFO, will host a conference call on the same day at 4:30 p.m. (Eastern) to discuss the results of the third fiscal quarter 2008, ended September 30, 2008. Management will also provide and update on market activity, including customers, new technologies, the FDA process, and pricing in addition to an update on the commercial production facility and growth plans for the business. After the presentation management will answer questions from the investor audience. To participate, dial toll-free 1-888-684-1277 or 1-913-312-1410 (international). The passcode is 1084482. The conference call will be webcast and can be accessed from the Company’s website at www.metabolix.com in the investor relations section.

To listen to a telephonic replay of the conference call, dial toll-free 1-888-203-1112 or 1-719-457-0820 for international callers and enter passcode 1084482. The replay will be available beginning at 7:30 p.m. (Eastern) on Wednesday, November 5, 2008 and will last through 11:59 PM (Eastern) November 12, 2008. In addition, the webcast will be archived on the Company’s website in the investor relations section.

About Metabolix

Founded in 1992, Metabolix, Inc. is an innovation driven bioscience company focused on providing sustainable solutions for the world’s needs for plastics, chemicals and energy. The Company is taking a systems approach, from gene to end product, integrating sophisticated biotechnology with advanced industrial practice. Metabolix is now developing and commercializing Mirel(TM) bioplastics, a sustainable and biodegradable alternative to petroleum-based plastics. Mirel is suitable for injection molding, extrusion coating, cast film and sheet, blown film and thermoforming. Metabolix is also developing a proprietary platform technology for co-producing plastics, chemicals and energy, from crops such as switchgrass, oilseeds and sugarcane.

For more information, please visit www.metabolix.com.

(MBLX-E)




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