October 5, 2009
Study may lead to new ulcer treatments
Spanish scientists say they've identified substances that can block a chemical pathway needed by bacteria that cause stomach ulcers and other diseases.
Professor Javier Sancho and colleagues at Zaragoza University said they knew from past research that blocking flavodoxin, a key protein needed by Helicobacter pylori bacteria for survival, could be the key to developing antibiotics specifically targeting the gastritis- and ulcer-causing bacteria.
These new inhibitors constitute promising candidates to develop new specific antibiotics against H. pylori, the researchers said.
The research is to be reported in the Oct. 16 issue of the journal Chemical Biology.