August 17, 2011
Virus Uses ‘Swiss Army Knife’ Protein To Cause Infection
In an advance in understanding Mother Nature's copy machines, motors, assembly lines and other biological nano-machines, scientists are describing how a multipurpose protein on the tail of a virus bores into bacteria like a drill bit, clears the shavings out of the hole and enlarges the hole. They report on the "Swiss Army Knife" protein, which enables the virus to pump its genetic material into and thus infect bacteria, in the Journal of the American Chemical Society.
Akio Kitao and colleagues focus on a group of viruses termed "bacteriophages," which literally means "bacteria eaters." These viruses infect bacteria like E. coli and usually make the bacteria dissolve. Infection involves injecting their own DNA or RNA into the bacteria, so that the viral genetic material takes over control of the bacteria. The tools for doing so are among numerous invisible nanomachines "” so small that 50,000 would fit across the width of a human hair "”that work unnoticed in organisms ranging from microbes to people.
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