Stem-Cell Research; Cardiac potential of adult stem cells reviewed
Posted on: Thursday, 26 February 2004, 06:00 CST
2004 MAR 7 - (NewsRx.com & NewsRx.net) -- The cardiac potential of adult stem cells has been reviewed.
"Adult cardiac muscle is unable to repair itself following severe disease or injury," scientists in the United States explained. "Because of this fundamental property of the myocardium, it was long believed that the adult myocardium is a postmitotic tissue."
"Yet, recent studies have indicated that new cardiac myocytes are generated throughout the life span of an adult and that extracardiac cells can contribute to the renewal of individual cells within the myocardium," according to L.M. Eisenberg and colleagues at the Medical University of South Carolina. "In addition, investigations of the phenotypic capacity of adult stem cells have suggested that their potential is not solely restricted to the differentiated cell phenotypes of the source tissue."
"These observations have great implications for cardiac biology, as stem cells obtained from the bone marrow and other readily accessible adult tissues may serve as a source of replacement cardiac myocytes," the researchers concluded.
Eisenberg and coauthors published their study in Anatomical Record Part A - Discoveries in Molecular Cellular and Evolutionary Biology (Adult stem cells and their cardiac potential. Anat Rec Part A, 2004;276A(1):103-112).
For additional information, contact L.M. Eisenberg, Medical University of South Carolina, Department of Cell Biology and Anatomy, BSB Room 654, 171 Ashley Avenue, Charleston, SC 29425, USA.
Publisher contact information for the journal Anatomical Record Part A - Discoveries in Molecular Cellular and Evolutionary Biology is: Wiley-Liss, Division John Wiley & Sons Inc., 605 Third Avenue, New York, NY 10158-0012, USA.
The information in this article comes under the major subject areas of Biotechnology, Cardiology, Cardiovascular Disease and Stem- Cell Research.
This article was prepared by Heart Disease Weekly editors from staff and other reports. Copyright 2004, Heart Disease Weekly via NewsRx.com & NewsRx.net.
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