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Last updated on April 23, 2014 at 1:22 EDT

Barrier To HIV Cure Bigger Than Previously Thought

October 24, 2013

HIV infection is typically treated with antiretroviral therapy, which targets actively replicating HIV but does not affect inactive or latent forms of the virus. The latent reservoir is the biggest barrier to curing HIV, and a study published by Cell Press October 24th in the journal Cell has shown that it could be 60 times larger than previously thought. The findings, publishing ahead of the upcoming translational medicine conference “What Will it Take to Achieve an AIDS-free World?” organized by Cell and The Lancet, highlight important limitations of current treatment strategies and could lead to the development of more effective interventions.

Credit: Cell, Ho et al.