Latest 5-alpha reductase Stories

2012-03-07 10:54:37

Men receiving testosterone supplementation who also received a drug (dutasteride) commonly used to treat an enlarged prostate gland and which blocks the conversion of testosterone to its potent metabolite DHT did not experience a significant difference in changes in certain outcomes such as muscle mass, muscle strength, or sexual function compared to men who did not receive dutasteride, according to a study in the March 7 issue of JAMA. Steroid 5α-reductase inhibitors, which...

2010-10-06 17:22:52

When compared with placebo and other drugs, long-term use of finasteride improves urinary tract symptoms associated with benign prostatic hyperplasia, and reduces disease progression. This conclusion comes from combining the findings of 23 randomized clinical trials that evaluated almost 21,000 men, and is published this month in The Cochrane Library. Finasteride is frequently given to men who have lower urinary tract symptoms (LUTS) such as frequent voiding at night (nocturia), incomplete...

2009-04-28 10:30:00

-- Data Presented at American Urological Association Annual Meeting -- SEATTLE and CHICAGO, April 28 /PRNewswire-FirstCall/ -- Researchers from Dendreon Corporation (Nasdaq: DNDN) today presented preclinical data demonstrating the potential of D-3263, Dendreon's orally bioavailable small molecule, which targets TRPM8 (a transmembrane cation channel protein), to treat benign prostatic hyperplasia (BPH). D-3263 demonstrated the ability to reduce BPH alone and in combination with finasteride,...

2009-02-27 22:32:32

Healthy men screened regularly for prostate cancer who show no symptoms should talk with doctors about a drug, new U.S. guidelines advise. The newly released joint guideline produced by the American Society of Clinical Oncology and the American Urological Association recommends that men with a prostate-specific antigen score of 3.0 or below who have no symptoms of the disease should discuss with doctors using a 5-alpha reductase inhibitor to prevent the disease. The 5-alpha reductase...

2008-10-14 00:00:41

Use of a class of medications for treating an enlarged prostate is not associated with an increased hip fracture risk, U.S. researchers said. Benign prostatic hyperplasia, or an enlarged prostate, is a common condition that affects some 8 million U.S. men and treatment includes surgical procedures, minimally invasive procedures and medications. Most often the first-line therapy is pharmacological, using either alpha-blockers, or 5-alpha reductase inhibitors such as finasteride or...

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