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Latest 5-HT2A receptor Stories

2013-10-08 10:09:58

For more than a decade the research group of Brown University Professor Walter Atwood has doggedly pursued the workings of the JC polyomavirus, which causes a disease called PML that fatally degrades the central nervous system of patients with weakened immune systems. In a study published online Oct. 2 in the Journal of Virology, his team describes how it gains entry into cells: It breaks in via certain receptors of the neurotransmitter serotonin called 5-HT2 receptors. Atwood, lead author...

2010-10-06 17:28:16

Findings could affect development of future depression, schizophrenia treatments Scripps Research Institute scientists have shown for the first time that the neurotransmitter serotonin uses a specialized signaling pathway to mediate biological functions that are distinct from the signaling pathways used by hallucinogenic substances. The new findings could have a profound effect on the development of new therapies for a number of disorders, including schizophrenia and depression. The study was...

2009-12-21 06:30:00

NEW YORK, Dec. 21 /PRNewswire/ -- Intra-Cellular Therapies, Inc. (ITI) announced at a recent conference on neuropsychiatric diseases the results from a recently completed Phase I clinical study demonstrating ITI-007, the Company's lead antipsychotic drug, interacts with important targets in the living human brain. These key targets are critical to drug action in many neuropsychiatric and related disorders. Using positron emission tomography (PET) to image receptor interactions, ITI-007...

2008-07-09 09:01:02

SAN DIEGO, July 9 /PRNewswire-FirstCall/ -- Arena Pharmaceuticals, Inc. today announced positive results from a multiple-ascending dose Phase 1b clinical trial of APD791 to evaluate the compound's safety, pharmacokinetics and pharmacodynamics. APD791 is Arena's internally discovered oral drug candidate intended for the treatment of arterial thrombosis and other related conditions. The Phase 1b trial was a randomized, double-blind, placebo-controlled, multiple-ascending dose trial in 50...

2008-05-01 16:50:04

Swiss chemist Albert Hofmann, who discovered the hallucinogenic drug LSD, died yesterday. But the LSD trip is far from over as scientists bring lucidity to how hallucinogens work. Also called psychedelics, hallucinogens alter a person's perception, mood and a slew of other mental processes. Hallucinogen history goes back centuries as people worldwide have taken the drugs to induce altered states for religious and spiritual purposes. While LSD (lysergic acid diethylamide),...


Word of the Day
drawcansir
  • A blustering, bullying fellow; a pot-valiant braggart; a bully.
This word is named for Draw-Can-Sir, a character in George Villiers' 17th century play The Rehearsal.
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