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Latest Candida albicans Stories

2013-11-04 09:14:59

Candida albicans is one of the leading causes of hospital-acquired infections in immune compromised patients. The risk of both developing candidiasis and the clinical outcome of infection is variable among patients, and the host-dependent factors that contribute to patient susceptibility to C. albicans infection are poorly understood. In this issue of the Journal of Clinical Investigation, Michail Lionakis and colleagues at the National Institute of Allergy and Infectious Diseases...

2013-09-12 11:34:04

A team of researchers at Cincinnati Children's Hospital Medical Center has developed an antibody that could prevent Candida infections that often afflict hospitalized patients who receive central lines. Margaret Hostetter, MD, director of infectious diseases at Cincinnati Children's, and her team developed the antibody, which prevents Candida albicans from binding to heparin, thereby stopping the formation of biofilm in a rat model of catheter-associated infection. A biofilm is a...

2013-09-03 10:55:46

Candida albicans is a common fungus found living in, and on, many parts of the human body. Usually this species causes no harm to humans unless it can breach the body's immune defences, where can lead to serious illness or death. It is known as an opportunistic pathogen that can colonise and infect individuals with a compromised immune system. New research, presented today at the Society for General Microbiology's Autumn Conference, gives us a greater understanding of how mucosal surfaces in...

2013-06-25 12:46:49

A new palm-sized microarray that holds 1,200 individual cultures of fungi or bacteria could enable faster, more efficient drug discovery, according to a study published in mBio®, the online open-access journal of the American Society for Microbiology. Scientists at the University of Texas at San Antonio and the U.S. Army Institute of Surgical Research at Fort Sam Houston have developed a microarray platform for culturing fungal biofilms, and validated one potential application of the...

2012-07-25 09:43:12

The opportunistic fungal pathogen Candida albicans inconspicuously lives in our bodies until it senses that we are weak, when it quickly adapts to go on the offensive. The fungus, known for causing yeast and other minor infections, also causes a sometimes-fatal infection known as candidemia in immunocompromised patients. An in vivo study, published in mBio, demonstrates how C. albicans can distinguish between a healthy and an unhealthy host and alter its physiology to attack. “The...

2012-03-17 00:00:51

Additional study identifies 224 new genetic interactors for key protein in Candida albicans Scientists at the University of Toronto have found a molecular mechanism that plays a key role in the transition of Candida albicans yeast into disease-causing fungus–one of the leading causes of hospital-acquired infection. The finding highlights the importance of heat in fungal growth, and provides a new target for drug therapies to counter Candida albicans infection. Candida albicans is...

2011-09-07 20:18:14

A six-year campaign to control invasive winter moths with a natural parasite led by entomologist Joe Elkinton of the University of Massachusetts Amherst now has concrete evidence that a parasitic fly, Cyzenis albicans, has been established and is attacking the pest at four sites in Seekonk, Hingham, Falmouth and Wellesley. It´s the beginning of the end for the decade-long defoliation of eastern Massachusetts trees by the invasive species, Elkinton says. The researchers marked an...

2011-01-24 18:23:29

The success of a fungal pathogen in becoming a persistent and opportunistic source of infection in human beings may be due to a mating strategy that can best be described as "don't be too choosy." A new Brown University study finds that Candida albicans will respond to the pheromones of several different species, not just its own, and if an opposite-sex partner isn't around, it can switch over to same-sex mating. In affairs of DNA exchange "” for the yeast has no heart "” Candida...

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2010-09-29 09:02:51

More than half of all people are hosts to Candida albicans in their bodies. This species might be located on their skin or mucous membranes or in the intestines "“ frequently without causing any symptoms. However, it can be dangerous to patients whose immunological system has been weakened such as after organ transplants or chemotherapy with cancer. Then, this fungus penetrates into deeper layers of tissue and uses the blood system to spread throughout the body. In Germany alone,...


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