News - Declaration of Helsinki
By Litton, Paul; Miller, Franklin G The central question in current debates about the moral appropriateness of randomized placebo-control trials and the principle of clinical equipoise for research is whether physician- researchers owe primary loyalty to their patient-subjects, as physicians owe their patients under medical care.
By Glass, Kathleen Cranley; Waring, Duff This article addresses medical negligence as a cause of action for harm to a research participant occasioned by withholding established, effective therapy in the placebo arm of a clinical trial, and the insufficiency of consent as a defense to such a claim.
By Fitzgerald, Daniel W; Wasunna, Angela We believe that by setting a positive goal, international ethical guidelines can help people understand the potential good that research does in resourcepoor countries, and may thereby encourage investigators to conduct more research to address the health problems of these poor populations.