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Latest ABC transporters Stories

2014-06-09 08:30:34

BANGALORE, India, June 9, 2014 /PRNewswire/ -- Clinigene International Ltd, a subsidiary of Syngene International Ltd, India's leading Contract Research Services provider, today announced that it has launched a cholesterol efflux assay to support global aspirants developing cholesterol lowering drugs. This biomarker assay is a cell based assay for assessing the ATP-binding cassette A1 (ABCA1) specific cholesterol efflux capacity in human serum samples. (Logo:...

Intracellular ABC Transporters Allow Leaf Beetle Larvae To Accumulate Defensive Substances When Feeding
2013-12-09 11:58:38

Max Planck Institute for Chemical Ecology Similar membrane proteins play a crucial role in the transport of toxic substances out of the cell Scientists at the Max Planck Institute for Chemical Ecology in Jena, Germany, have discovered the decisive biological stimulator for the accumulation of defensive substances in leaf beetle larvae used by the insects to fend off predators: ABC transport proteins, which are found in large quantities in glandular cells of the larvae. The poplar leaf...

How Membrane Transporter Moves
2013-12-03 09:50:42

University of Illinois Researchers have tried for decades to understand the undulations and gyrations that allow transport proteins to shuttle molecules from one side of a cell membrane to the other. Now scientists report that they have found a way to penetrate the mystery. They have worked out every step in the molecular dance that enables one such transporter to do its job. The new findings, reported in the Proceedings of the National Academy of Sciences, will help scientists figure...

2013-10-03 23:03:42

Qualyst Transporter Solutions completed the Transporter Certified™ program using two lots of high quality cryoplateable human hepatocytes from XenoTech. Using Transporter Certified™ hepatocytes means users can be sure their cells will maintain a fully functioning complement of hepatic transporters, reflect in vivo-relevant intracellular concentrations of drugs and produce in vivo relevant results. Lenexa, KS (PRWEB) October 03, 2013 XenoTech, LLC and Qualyst Transporter Solutions,...

2013-09-11 23:20:17

ChanTest is a world leader in drug safety and discovery, in areas particularly relevant to Cystic Fibrosis. Cleveland, OH (PRWEB) September 11, 2013 The world is still looking for meaningful solutions to address the pain and suffering of patients with Cystic Fibrosis. On Thursday, September 12, ChanTest will be hosting a complimentary webinar entitled “Unfolding Cystic Fibrosis Research,” to share important information in this field. The event will include presentations by Dr....

2013-07-18 23:18:21

ChansPorter™ Assays, developed by ChanTest, provide the best means possible for measuring the functional activity of important pharmaceutical targets, including the Cystic Fibrosis Transmembrane conductance Regulator (CFTR). Cleveland, OH (PRWEB) July 18, 2013 The new ChansPorter™ Assays provide faster and more accurate answers. Using human (patient-derived) bronchial epithelia, and incorporating higher throughput into the discovery screening and profiling processes increases...

2013-07-08 12:16:08

University of Toronto researchers are helping demystify an important class of proteins associated with disease, a discovery that could lead to better treatments for cancer, cystic fibrosis and many other conditions. Igor Stagljar, Professor in the Faculty of Medicine's Donnelly Centre for Cellular and Biomolecular Research, and his team developed the first roadmap for ATP-binding cassette (ABC) transporter proteins. These proteins are crucial components of every cell, and are also involved...

2013-03-22 09:42:47

Data about defective regulatory protein described in Proceedings of the National Academy of Sciences A little more than a year after the FDA approved Kalydeco (Vx-770), the first drug of its kind to treat the underlying cause of cystic fibrosis, University of Missouri researchers believe they have found exactly how this drug works and how to improve its effectiveness in the future. Described in the current issue of the Proceedings of the National Academy of Sciences, MU researchers have...


Word of the Day
attercop
  • A spider.
  • Figuratively, a peevish, testy, ill-natured person.
'Attercop' comes from the Old English 'atorcoppe,' where 'atter' means 'poison, venom' and‎ 'cop' means 'spider.' 'Coppa' is a derivative of 'cop,' top, summit, round head, or 'copp,' cup, vessel, which refers to 'the supposed venomous properties of spiders,' says the OED. 'Copp' is still found in the word 'cobweb.'
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