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Latest Abcg2 Stories

2010-06-18 14:20:41

The expression of a transporter protein called the Breast Cancer Resistance Protein (BCRP) in rheumatoid arthritis (RA) patients may indicate higher disease activity and could be a barrier to the effectiveness of disease-modifying antirheumatic drugs (DMARDs), according to the results of a study presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy. In a Turkish study, researchers analysed specimens of synovium (the soft tissue that lines...

2009-06-24 13:13:56

U.S. scientists say a gene previously identified as causing gout can lead to high concentrations of blood urate that forms crystals in joint tissues. Johns Hopkins University researchers were part of an international team that surveyed the genomes of 12,000 individuals to find the genetic cause for gout. Now the Johns Hopkins scientists have shown the malfunctioning gene, ABCG2, can lead to high concentrations of blood urate that causes joint inflammation and pain -- the hallmark of the...

2009-06-19 09:18:07

Having partnered last year with an international team that surveyed the genomes of 12,000 individuals to find a genetic cause for gout, Johns Hopkins scientists now have shown that the malfunctioning gene they helped uncover can lead to high concentrations of blood urate that forms crystals in joint tissue, causing inflammation and pain "” the hallmark of this disease. The ABCG2 gene, they found, makes a protein that normally transports urate out of the kidney and into urine before the...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.