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Latest ACE inhibitor Stories

2009-11-17 07:00:00

Study highlights: -- A study of nearly 4,000 heart failure patients finds that a larger dose of angiotensin receptor blockers (ARBs) works better than a smaller dose. -- The higher dose was associated with a 10.1 percent relative risk reduction (in the combined primary end-point of all-cause mortality and hospitalization for heart failure) versus the lower dose, mostly due to a reduction in the risk of heart failure hospitalizations. -- There was no significant difference in all-cause...

2009-11-17 02:00:00

LEIDEN, The Netherlands, November 17 /PRNewswire/ -- Top Institute Pharma (TI Pharma) has formed a consortium with Actelion Pharmaceuticals Ltd, Erasmus Medical Centre and Maastricht University to define new modalities for the treatment of hypertension (high blood pressure) and associated vascular complications such as heart and kidney failure, myocardial infarction and stroke. Based on novel action mechanisms, new drugs may be discovered with the potential to prevent vascular...

2009-10-19 18:06:00

ROCKVILLE, Md., Oct. 19 /PRNewswire-USNewswire/ -- Two medications commonly used to treat high blood pressure appear to be effective in treating a common type of heart disease known as stable ischemic heart disease, according to a new comparative effectiveness review funded by HHS' Agency for Healthcare Research and Quality. A version of the analysis was posted in the October 20 online version of the Annals of Internal Medicine. Treatment featuring the two medications -- inhibitors of...

2009-09-17 15:05:00

EAST HANOVER, N.J., Sept. 17 /PRNewswire/ -- The US Food and Drug Administration (FDA) has approved Valturna((R)) (aliskiren and valsartan) tablets, the first and only medicine to target two key points within the renin system, also known as the renin angiotensin aldosterone system (RAAS), an important regulator of blood pressure. This is the first approval for Valturna, which is indicated for the treatment of high blood pressure in patients not adequately controlled on aliskiren or...

2009-09-17 15:05:00

EAST HANOVER, N.J., Sept. 17 /PRNewswire/ -- The US Food and Drug Administration (FDA) has approved Valturna(R) (aliskiren and valsartan) tablets, the first and only medicine to target two key points within the renin system, also known as the renin angiotensin aldosterone system (RAAS), an important regulator of blood pressure. This is the first approval for Valturna, which is indicated for the treatment of high blood pressure in patients not adequately controlled on aliskiren or...

2009-08-18 15:00:00

 A mutation in a gene that helps regulate high blood pressure is a cause of inherited kidney disease, according to a new study by researchers at Wake Forest University School of Medicine, Charles University in Prague and colleagues.The discovery provides insight into a protein, renin, that is important in blood pressure regulation, and reveals the cause of one type of inherited kidney disease occurring in adults and children, said co-investigator Anthony Bleyer, M.D., professor of...

2009-07-27 08:37:13

Proven beneficial to the heart and kidneys, research shows certain blood pressure drugs called ACE inhibitors may also benefit the brain.A specific type of ACE inhibitor known as "centrally acting" can cross the blood-brain barrier. A study involving 5,888 participants over the age of 65 analyzed the effect of centrally acting ACE inhibitors, finding lower rates of mental decline in patients who took the drugs. In addition, participants exposed to the drugs saw 65 percent less cognitive...

2009-05-13 07:08:00

Fixed-dose combination offers a convenient option that may help patients reduce steps to reach their blood pressure goals while decreasing patient pill burden(1) PARSIPPANY, N.J., May 13 /PRNewswire/ -- Daiichi Sankyo, Inc. today announced that the United States Food and Drug Administration (FDA) has approved the combination treatment AZOR(R) (amlodipine and olmesartan medoxomil) as initial or 'first-line' therapy in patients likely to need multiple antihypertensive agents to achieve their...

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2009-03-20 09:39:48

A newly published study found patients actually have more control of their high blood pressure (hypertension) when treated with less medication. The study led by Dr. Ross D. Feldman, a clinical scientist with the Robarts Research Institute at The University of Western Ontario recommends a simplified and more effective method of treating hypertension using low doses of single pill combinations, rather than multiple pills. The "Simplified Treatment Intervention to Control Hypertension" (STITCH)...

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2009-02-23 11:03:28

Researchers in Canada are reporting evidence that eggs "” often frowned upon for their high cholesterol content "” may reduce another heart disease risk factor "” high blood pressure. They describe identification of egg proteins that act like a popular group of prescription medications in lowering blood pressure. The report appeared in the Feb. 11 issue of ACS' Journal of Agricultural and Food Chemistry, a bi-weekly publication. In the new study, Jianping Wu and Kaustav...