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Latest ACE inhibitors Stories

2008-06-25 03:01:35

By Popov, A F Hinz, J; Liakopoulos, O J; Schmitto, J D; Seipelt, R; Quintel, M; Schoendube, F A Aim. The angiotensin I-converting enzyme insertion/deletion polymorphism (ACE-I/D), including three genotypes (II, ID, DD), with a known impact on midterm mortality and morbidity in patiente after coronary artery bypass graft surgery (CABG), was studied. Since this polymorphism has been linked with increased vascular response to phenylephrine during cardiopulmonary bypass (CFB), we investigated...

2008-06-24 02:30:29

Glenmark Generics, a subsidiary of Glenmark Pharmaceuticals, has received ANDA approval from the FDA for Trandolapril tablets USP 1mg, 2mg and 4mg and will immediately commence marketing and distribution of these products in the US market. Glenmark's Trandolapril is an angiotensin converting enzyme inhibitor used to treat high blood pressure and is the generic equivalent of Mavik tablets marketed by Abbott Laboratories. This recent approval coupled with the three abbreviated new drug...

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2008-03-31 13:05:00

Telmisartan is as effective as ramipril in reducing cardiovascular deathA major Canadian-led global study has found that a new blood pressure medication is effective in reducing cardiovascular death, with fewer side effects than the current standard of care. The study found a new drug telmisartan is as effective as the popular drug ramipril in reducing cardiovascular death in high risk patients and it has fewer side effects.Dr. Salim Yusuf, director of the Population Health Research Institute...

2008-03-31 12:00:11

CHICAGO, March 31 /PRNewswire/ -- Interim results from the ACCOMPLISH (Avoiding Cardiovascular Events through COMbination Therapy in Patients LIving with Systolic Hypertension) trial demonstrate that high-risk, high blood pressure patients treated with Lotrel(R) (amlodipine besylate and benazepril HCl) had 20% fewer cardiovascular events than those taking a benazepril and hydrochlorothiazide (HCTZ) combination. This is the first cardiovascular outcomes trial in a hypertensive population...

2007-08-02 06:16:50

By Meredith, Peter A Key words: Candesartan - Cardiovascular disease - Heart failure - Hypertension ABSTRACT Therapeutic interventions that block the renin-angiotensin- aldosterone system (RAAS) have an important role in slowing the progression of cardiovascular risk factors to established cardiovascular diseases. In recent years, angiotensin receptor blockers (ARBs) have emerged as effective and well-tolerated alternatives to an anglotensin-converting enzyme Inhibitor (ACEi) for RAAS...

2007-06-10 06:00:11

By Telejko, Elwira Key words: Acceptability - L-Arginine - Bioequivalence - Perindopril - Shelf life - Stability ABSTRACT Background: The efficacy of the angiotensin-converting enzyme (ACE) inhibitor perindopril in the treatment of hypertension, stable coronary artery disease, and heart failure is well established. The reduced stability of the current salt, perindopril-tert-butylamine, in extreme climatic conditions has prompted research into more stable compounds. This article presents...

2007-04-24 18:00:36

A British study confirming the safety of the drug Lisinopril could help people who have suffered a stroke. High blood pressure is common immediately after a stroke and such patients tend to have a worse outcome than those with normal blood pressure. Therefore, scientists believe it might be helpful to have a drug available that would lower blood pressure immediately after a stroke occurs. However, trials to date have shown variable results, probably because treatment was either started...

2006-10-22 03:00:10

By Holzgreve, Heinrich; Risler, Teut; Trenkwalder, Peter Key words: Combination drug therapy - Hypertension - Indapamide - Perindopril - Risk factors ABSTRACT Background: Tight blood pressure (BP) control is required to reduce cardiovascular morbidity and mortality. Objective: To evaluate the efficacy and tolerability of the first line combination perindopril/indapamide in hypertension in daily practice. Design and methods: In this prospective, open-label, observational trial, 1892...

2006-06-07 22:58:27

NEW YORK (Reuters Health) - When pregnant women take ACE inhibitor medication during their first trimester, the risk of the infants having major malformations is more than doubled, according to a study in this week's New England Journal of Medicine. Angiotensin-converting-enzyme (or ACE) inhibitors are widely used to treat high blood pressure, and are often prescribed for people with diabetes. Many formulations are available, sold under numerous brand names. "Exposure to ACE...

2006-05-05 10:30:30

NEW YORK (Reuters Health) - Compared with patients of other ethnicities, black and East Asian patients are at increased risk for various adverse reactions when taking cardiovascular drugs, according to a report in the British Medical Journal. Ethnic group "may be one determinant of harms of a given treatment in the individual patient, either because it acts as a surrogate measure of genetic make up or because cultural factors alter the risk," senior author Dr. Robin E. Ferner and...


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ramage
  • Boughs or branches.
  • Warbling of birds in trees.
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