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Last updated on April 17, 2014 at 16:09 EDT

Latest Acetaldehyde dehydrogenase Stories

2010-01-10 13:16:44

An experimental compound repaired a defective alcohol metabolism enzyme that affects an estimated 1 billion people worldwide, according to research supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The findings, published Jan. 10, 2010 in the advance online edition of Nature Structural and Molecular Biology, suggest the possibility of a treatment to reduce the health problems associated with the enzyme defect. "This intriguing finding could have broad public health...

2008-09-09 03:00:06

By Venkataranganna, M V Gopumadhavan, S; Sundaram, R; Peer, Ghouse; Mitra, S K Background & objectives: PartySmart is a herbal preparation intended for the management of alcohol hangover and other related toxic effects in clinical situation. The present study was designed to investigate the pharmacodynamics and oral toxicity of PartySmart, a herbal formulation in rats. Methods: Effect of PartySmart on blood acetaldehyde and alcohol levels was evaluated at doses of 125, 250 and 500 mg/kg...

2005-07-15 12:38:23

This mutation is no party, Japanese team say HealthDay News -- Many hangover sufferers looking for someone or something to blame can now point the finger at their own genes, according to a new study. Mutations in a specific gene inactivate a key enzyme and slow the elimination of acetaldehyde -- the first product of alcohol metabolism -- from the body, say Japanese researchers reporting in the July issue of Alcoholism: Clinical & Experimental Research. Their study of 326 Japanese female...