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Latest Acetylcholine receptor Stories

2013-12-16 12:10:42

Research indicates e-cigarettes may not significantly reduce risk for heart disease Nicotine, the major addictive substance in cigarette smoke, contributes to smokers' higher risk of developing atherosclerosis, the primary cause of heart attacks, according to research to be presented Sunday, Dec. 15, at the American Society for Cell Biology Annual Meeting in New Orleans. These findings suggest that e-cigarettes, the battery-powered devices that deliver nicotine in steam without the...

2012-01-10 21:35:36

Control of a “blind” neuroreceptor with an optical switch When nerve cells communicate with one another, specialized receptor molecules on their surfaces play a central role in relaying signals between them. A collaborative venture involving teams of chemists based at Ludwig-Maximilians-Universität (LMU) in Munich and the University of California in Berkeley has now succeeded in converting an intrinsically “blind” receptor molecule into a...

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2011-08-19 10:00:08

Researchers at the Faculty of Pharmaceutical Sciences at the University of Copenhagen have collaborated with the company NeuroSearch to generate new knowledge about an important part of the brain's complex communication system. The discovery could form the basis for future development of better medicines for patients with psychiatric disorders. The results were recently published Journal of Neuroscience. New knowledge challenges established scientific ideas about the function of the...

2011-06-03 12:19:13

Using a high-resolution single-molecule study technique, University of Illinois researchers have seen the very subtle differences between two branches of an important family of neurotransmitter-gated ion channels. Professor Claudio Grosman and research scientist Gisela Cymes published their work in the journal Nature. Nicotinic-type receptors are proteins embedded in the membranes of nerve and muscle cells that regulate activity. A neurotransmitter, such as acetylcholine, triggers a small...

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2011-01-31 09:10:00

Experts at the Scripps Research Institute campus in Florida have found a genetic mechanism that controls nicotine addiction in the brain--a discovery which could open the door for more effective smoking cessation aids. Lead researcher Paul Kenny, an associate professor with Scripps Research, and colleagues analyzed protein molecules known as nicotinic acetylcholine receptors, or nAChRs. Specifically, they were looking at nAChRs that contained a specific subunit, ÃŽ±5, in...

2010-08-24 13:57:19

When nicotine binds to the nicotinic acetylcholine receptor (nAchR), it is known to promote smoking addiction and may also directly promote the development of breast cancer, according to a study published online August 23 in The Journal of the National Cancer Institute. While smoking is a well-known risk factor for a broad range of cancer types, non-nicotine components of tobacco have generally been thought to be the carcinogens, so little is known about how nicotine acts on cells to promote...

2009-04-06 16:17:59

Nicotine isn't just addictive, it may also interfere with dozens of cellular interactions in the body, U.S. researchers suggest. Brown University researchers say the data could help scientists develop better treatments for various diseases. It opens several new lines of investigation, lead author Edward Hawrot says in a statement. Hawrot and a team that included graduate students William Brucker and Joao Paulo looked specifically at the alpha-7 nicotinic acetylcholine receptor in mouse brain...

2009-03-24 09:18:54

-A tiny genetic mutation is the key to understanding why nicotine--which binds to brain receptors with such addictive potency--is virtually powerless in muscle cells that are studded with the same type of receptor. That's according to California Institute of Technology (Caltech) researchers, who report their findings in the March 26 issue of the journal Nature.By all rights, nicotine ought to paralyze or even kill us, explains Dennis Dougherty, the George Grant Hoag Professor of Chemistry at...

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2008-11-18 09:25:18

Scientists have identified a relationship between two proteins in the brain that has links to both nicotine addiction and autism. The finding has led to speculation that existing drugs used to curb nicotine addiction might serve as the basis for potential therapies to alleviate the symptoms of autism. The discovery identified a defining role for a protein made by the neurexin-1 gene, which is located in brain cells and assists in connecting neurons as part of the brain's chemical...


Word of the Day
Cthulhu
  • A gigantic fictional humanoid alien god being described with a head resembling an octopus and dragon wings and claws, around whom an insane cult developed.
  • Pertaining to the mythos of Cthulhu and additional otherworldly beings created by H. P. Lovecraft or inspired by his writings and imitators.
This word was invented in 1926 by H.P. Lovecraft for his short story, 'The Call of Cthulhu.' 'Cthulhu' may be based on the word 'chthonic,' which in Greek mythology refers to the underworld.
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