Latest Acetylcholine Stories

New study finds that older people hospitalized for bradycardia are more likely to be taking cholinesterase-inhibiting drugs such as donepezilPeople taking one of several drugs commonly prescribed to treat Alzheimer's disease are more likely to be hospitalized for a potentially serious condition called bradycardia than patients not taking these medications.Researchers from St. Michael's Hospital and Ontario's Institute for Clinical Evaluative Sciences (ICES) analyzed data from 1.4 million...

NEW YORK, Sept. 10 /PRNewswire/ -- NexGenix Pharmaceuticals Holdings, Inc. (Privately Held) today announced that Chief Executive Officer Dr. Allan E. Rubenstein will be presenting at two industry conferences during the month of September. The first presentation will take place on September 11th, 2009 at 11:40am as part of the Rodman & Renshaw 11th Annual Healthcare Conference in New York, New York. The second presentation will take place on September 23, 2009 at 4:15pm as part of the...

 The polyphenols found in red wine are thought to help prevent Alzheimer's disease, and new research from Purdue University and Mount Sinai School of Medicine has shown that some of those compounds in fact reach the brain.Mario Ferruzzi, a Purdue associate professor of food science; Connie Weaver, Purdue's head of foods and nutrition; and Elsa Janle, a Purdue associate professor of foods and nutrition, found that the amount of polyphenols from grapeseed extract that can reach a rat's brain...

A study released on Wednesday warned that one of the world's most common insect repellents acts on the central nervous system in the same way as some insecticides and nerve gases, AFP reported.Researchers say moderate use of the chemical compound deet is most likely safe, but experiments on insects, as well as on enzymes extracted from mice and human neurons, showed for the first time that it can interfere with the proper functioning of the nervous system.Many experts are urgently calling for...

OSCEOLA, Wis., Aug. 4 /PRNewswire/ -- NeuroScience, Inc. has launched a new product -- Avipaxin -- aimed at decreasing elevated levels of pro-inflammatory cytokines. Avipaxin supports acetylcholine levels by providing substrates for its production and by inhibiting its metabolizing enzyme, acetylcholinesterase. Initial studies at NeuroScience, Inc. revealed a significant decrease in pro-inflammatory cytokines and chemokines after Avipaxin use. These studies also revealed a decrease in the...

Barrow Neurological Institute researchers have identified a novel receptor in the brain that is extremely sensitive to beta-amyloid peptide (AB) and may play a key role in early stages of Alzheimer's disease.Published in the Journal of Neuroscience, the research lead by Jie Wu, MD, PhD, has identified a new candidate for therapeutic intervention in Alzheimer's.The novel receptor was found in the basal forebrain, an area of the brain that plays a critical role in memory and learning and is one...

VIENNA, July 15 /PRNewswire/ -- EnVivo Pharmaceuticals today announced the successful completion of a phase Ib/IIa trial in Alzheimer's disease patients with its nicotinic alpha-7 agonist EVP-6124. Subjects receiving EVP-6124 experienced improvement in cognition and EVP-6124 showed good tolerability and safety. The announcement came at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD) in Vienna, Austria where EnVivo presented its findings. EVP-6124 is...

WATERTOWN, Mass., July 7 /PRNewswire/ -- WHAT: EnVivo Pharmaceuticals to share results from its Ib/IIa trial in Alzheimer's disease patients with its nicotinic alpha-7 agonist EVP-6124. WHEN: Wednesday, July 15, 2009. WHERE: Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD) in Vienna, Austria. WHO: Dana Hilt, MD, senior vice president,...

A study published this week in the open access journal PLoS Medicine finds no evidence to suggest that a controversial antidote recommended by the World Health Organisation (WHO) to treat patients poisoned with highly toxic insecticides improves their chance of survival. The results may even add weight to existing concerns about pralidoxime, the treatment recommended by the WHO, by suggesting that it could be harmful in patients who have deliberately poisoned themselves with...

Drugs -- many over-the-counter -- for allergies, hypertension or asthma can cause cognition problems in the elderly, U.S. researchers found. Study author Dr. Malaz Boustani of the Indiana University School of Medicine and Regenstrief Institute and colleagues conducted an analysis of 27 peer-reviewed studies of the relationship of the anti-cholinergic effect in some drugs -- a toxic reaction -- and brain function. Many medications used for several common disease states have anti-cholinergic...