Latest Actin Stories
Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have discovered that a protein, zyxin, is necessary for the maintenance and repair of the cell's cytoskeleton, or internal framework, which serves as the muscle and bone of the cell.
Scientists at Emory University School of Medicine have uncovered how a structural component inside neurons performs two coordinated dance moves when the connections between neurons are strengthened.
For the casual observer it is fascinating to watch the orderly and seemingly choreographed motion of hundreds or even thousands of fish, birds or insects.
Functioning much like gears in a machine, cellular motor proteins are critical to dynamic functions throughout the body, including muscle contraction, cell migration and cellular growth processes.
Scientists from the Florida campus of The Scripps Research Institute have discovered a mechanism that plays a critical role in the formation of long-term memory.
In this study, Shuichi Takeda at Nagoya University and colleagues present the X-ray crystal structures of the actin capping protein (CP) complexed with its inhibitors, V-1 and CARMIL, and demonstrate that the two regulators modulate the filament capping activity in very different manners.
There are major shifts underway in understanding the physiological mechanisms that control muscle contraction, a field that has been the focus of intense research for centuries.
The APC protein serves as the colon's guardian, keeping tumors at bay.
University of Pennsylvania bioengineers have demonstrated that the cells that line blood vessels respond to mechanical forces â€” the microscopic tugging and pulling on cellular structures â€” by reinforcing and growing their connections, thus creating stronger adhesive interactions between neighboring cells.
Cancer cells need all three of their cytoskeletonsâ€”actin, microtubules, and intermediate filamentsâ€”to metastasize, according to a study published online on April 26 in the Journal of Cell Biology.
- A hairdresser.