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Latest Actin Stories

2009-09-14 08:31:11

A network of proteins underlying the plasma membrane keeps epithelial cells in shape and maintains their orderly hexagonal packing in the mouse lens, say Nowak et al. The study will appear in the September 21, 2009 issue of the Journal of Cell Biology (online September 14). Spectrin, F-actin, and associated proteins form a meshwork that supports and shapes the plasma membrane of red blood cells. A similar network underlies the membranes of other cell types, including lens fiber cells:...

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2009-09-11 07:58:32

Every moment, millions of a body's cells flawlessly divvy up their genes and pinch perfectly in half to form two identical progeny for the replenishment of tissues and organs "” even as they collide, get stuck, and squeeze through infinitesimally small spaces that distort their shapes. Now Johns Hopkins scientists, working with the simplest of organisms, have discovered the molecular sensor that lets cells not only "feel" changes to their neat shapes, but also to remodel themselves back...

2009-07-21 19:15:00

Cells rely on tiny molecular motors to deliver cargo, such as mRNA and organelles, within the cell. The critical nature of this transport system is evidenced by the fact that disruption of motors by genetic defects leads to fatal diseases in humans. Although investigators have isolated these motor to study their function in a controlled environment outside the cell, it has been difficult for researchers to follow these fascinating molecular transporters in their natural environment, the...

2009-07-15 12:40:00

Understanding how neurons migrate to their proper place during brain development will offer insights into how malfunctions in the machinery cause epilepsy and mental retardation MEMPHIS, Tenn., July 15 /PRNewswire-USNewswire/ -- The molecular machinery that helps brain cells migrate to their correct place in the developing brain has been identified by scientists at St. Jude Children's Research Hospital. The finding offers new insight into the forces that drive brain organization in...

2009-07-15 13:40:00

Understanding how neurons migrate to their proper place during brain development will offer insights into how malfunctions in the machinery cause epilepsy and mental retardationThe molecular machinery that helps brain cells migrate to their correct place in the developing brain has been identified by scientists at St. Jude Children's Research Hospital. The finding offers new insight into the forces that drive brain organization in developing fetuses and children during their first years....

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2009-07-13 10:55:00

New study helps explain why it is easy to encode new memories but hard to hold onto themMemories aren't made of actin filaments. But their assembly is crucial for long-term potentiation (LTP), an increase in synapse sensitivity that researchers think helps to lay down memories. In the July 13, 2009 issue of the Journal of Cell Biology (www.jcb.org), Rex et al. reveal that LTP's actin reorganization occurs in two stages that are controlled by different pathways, a discovery that helps explain...

2009-06-22 09:54:37

"“ Notch signaling helps determine the fate of a number of different cell types in a variety of organisms, including humans. In an article that appears in the current issue of Nature Cell Biology, researchers at Baylor College of Medicine report that a new finding about the Notch signaling pathway in sensory organ precursor cells in the fruit fly could explain the mystery behind an immunological disorder called Wiskott-Aldrich syndrome."This finding provides a model for how Wiskott...

2009-06-15 14:33:39

DNA might be the blueprint for living things, but proteins are the builders. Researchers trying to understand how and which proteins work together have developed a new crosslinking tool that is small and unobtrusive enough to use in live cells. Using the new tool, the scientists have discovered new details about a well-studied complex of proteins known as RNA polymerase. The results suggest the method might uncover collaborations between proteins that are too brief for other techniques to...

2009-06-08 11:36:41

During desperate times, such as fasting, or muscle wasting that afflicts cancer or AIDS patients, the body cannibalizes itself, atrophying and breaking down skeletal muscle proteins to liberate amino acids. In a new study published online June 8 and in the June 15, 2009 print issue of the Journal of Cell Biology (www.jcb.org), Shenhav Cohen, Alfred Goldberg, and colleagues show that muscle atrophy is a more ordered process than was previously thought. These researchers find evidence that...

2009-05-27 14:09:00

Advanced Control Systems Enable Robotic Oil and Natural Gas Drilling CAMBRIDGE, Mass., May 27 /PRNewswire/ -- Seabed Rig AS has licensed technology and contracted with Energid Technologies Corporation to create a robot control system for its next-generation automated drilling and exploration platforms. Seabed Rig AS is developing a new autonomous drilling rig that operates in ultra deep water and arctic environments. Unlike traditional surface operations, the new rigs will lie on the ocean...


Word of the Day
ambsace
  • Bad luck; misfortune.
  • The smallest amount possible or the most worthless thing.
The word 'ambsace' comes from a Latin word meaning 'both'.