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Latest Actin Stories

2009-05-25 09:34:15

In a world first, West Australian scientists have cured mice of a devastating muscle disease that causes a Floppy Baby Syndrome "“ a breakthrough that could ultimately help thousands of families across the globe. The research, published online today in the Journal of Cell Biology, reveals how a team at the Western Australian Institute for Medical Research (WAIMR) has restored muscle function in mice with one type of Floppy Baby Syndrome "“ a congenital myopathy disorder that...

2009-03-31 08:10:31

U.S. cancer researchers say they've identified a molecule known as protein kinase D1 that is key to enabling a tumor cell to metastasize. Mayo Clinic scientists in Florida say the finding may lead to a technique that can stop cancer from spreading elsewhere in the body -- the process that most often leads to death. The researchers, led by cancer biologist Peter Storz, found that if PKD1 is active, tumor cells cannot move, a finding they say explains why PKD1 is silenced in some invasive...

2009-03-19 10:46:15

HZI researchers identify molecular signal pathway in diarrhea illnesses The bacterium Escherichia coli is part of the healthy human intestinal flora. However, E. coli also has pathogenic relatives that trigger diarrhea illnesses: enterohemorrhagic E.coli bacteria. During the course of an infection they infest the intestinal mucosa, causing injury in the process, in contrast to benign bacteria. The EHECs adhere to the surface of the mucosal cells and alter them internally: a part of the...

2009-03-16 13:18:30

U.S. medical scientists say they have discovered a new method to prevent bacterial infections by using the body's own enzymes. Dr Quinn Parks and colleagues at Denver's National Jewish Health Hospital said they used enzymes against products of the body's own defense cells to prevent Pseudomonas aeruginosa bacteria from building a protective biofilm that enables the bacteria to avoid both the body's immune mechanisms and antibiotics. When the body's defense cells, called neutrophils, attack P....

2009-01-14 06:18:27

A protein that was first identified for playing a key role in regulating normal heart rhythms also appears to be significant in helping muscle cells survive the forces of muscle contraction. The clue was a laboratory mouse that seemed to have a form of muscular dystrophy. A group of proteins called ankyrins, or anchor proteins, were first discovered in human red blood cells by Vann Bennett, M.D. a Howard Hughes Medical Institute investigator and James B. Duke Professor of Cell Biology,...

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2008-12-09 10:19:28

Researchers from the Ludwig Institute for Cancer Research at the University of California, San Diego School of Medicine have identified a key step required for cell division in a study that could help improve therapies to treat cancer. Their work describing the mechanism of the contractile ring "“ a structure that pinches the mother cell into two daughter cells "“ has been published in the December 5 issue of the journal Science. The division of one cell into two is accomplished...

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2008-11-25 11:40:00

Flip open any biology textbook and you're bound to see a complicated diagram of the inner workings of a cell, with its internal scaffolding, the  cytoskeleton, and how it maintains a cell's shape. Yet the fundamental question remains, which came first: the shape, or the skeleton?Now a research team led by Phong Tran, PhD, Assistant Professor of Cell and Developmental Biology at the University of Pennsylvania School of Medicine, has the answer: Both.The findings, published online this...

2008-06-27 06:02:23

By Dinh, Anh-Tuan Pangarkar, Chinmay; Mitragotri, Samir Unlike macroscopic problems in mass, energy and momentum transfer, which are described by continuum equations, the movements and interactions of the nanoscale entities within a cell constitute a transport phenomenon known as discrete nanoscale transport (DNT). Imagine yourself on an alien spaceship, watching the daily goings- on of a large city through a telescope. You would see (among other things) complex transportation systems...

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2008-04-10 14:20:00

Researchers at the University of Pennsylvania School of Medicine have discovered that a protein called leiomodin (Lmod) promotes the assembly of an important heart muscle protein called actin. What's more, Lmod directs the assembly of actin to form the pumping unit of the heart. The findings appear in this week's issue of Science."Very little was known about Lmod when we began this study," says lead author Roberto Dominguez, PhD, Associate Professor of Physiology. "It appeared that this...

2005-11-23 13:28:28

Researchers at the Albert Einstein College of Medicine and the German Cancer Research Institute have shown how protein synthesis is targeted to certain regions of a cell--a process crucial for the cellular motility that governs nerve growth, wound healing and cancer metastasis. Their study appears in the November 24 issue of the journal Nature. Led by Drs. Robert Singer and Dr Stefan Huettelmaier, the research team focused on migrating fibroblast cells important in wound healing. To move...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.