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Last updated on April 24, 2014 at 21:24 EDT

Latest Acute liver failure Stories

2014-04-11 00:21:56

LONDON, April 11, 2014 /PRNewswire/ -- - Hepatic encephalopathy (HE) is associated with a significant increase in mortality (58.1% vs. 32.4%), as well as longer hospital stays (8 days vs. 6.8 days) and more primary care visits (18.2 vs. 8.7 contacts per patient year) compared to similar liver patients without HE[i],[ii] - XIFAXAN(R) 550 (rifaximin-alpha) is a cost-effective treatment option for the...

2014-04-10 13:40:50

In the UK paracetamol toxicity is the most common cause of ALF and has a high mortality rate. It is estimated that 150 to 200 deaths and 15 to 20 LTs occur as a result of poisoning each year in England and Wales. LT is the definitive treatment for ALF patients who meet the criteria for transplantation but the current means of selection for LT (the King's College Criteria) are not ideal and do not assess changes in prognostic measures over time or quantify the mortality risk for individual...

2014-02-26 23:27:54

National network of attorneys continues to provide complimentary consultations to consumers inquiring about legal options to seek compensation over allegations that Tylenol and other acetaminophens may cause liver damage. San Diego, Ca (PRWEB) February 26, 2014 http://www.resource4thepeople.com/defectivedrugs/acetaminophen.html Resource4thePeople announced today it is alerting consumers to a safety alert* issued by the Food and Drug Administration warning health care professionals to...

2013-12-09 08:30:25

Presentations examine role of OFIRMEVĀ® (acetaminophen) injection in improving outcomes and cost of care for treating acute pain associated with common joint replacement procedures ORLANDO, Fla., Dec. 9, 2013 /PRNewswire/ -- Cadence Pharmaceuticals, Inc. (NASDAQ: CADX), a biopharmaceutical company focused on acquiring, in-licensing, developing and commercializing proprietary products principally for use in the hospital setting, announced today that results from a new study analyzing...

2013-11-04 08:27:33

Presented: November 5, 2013 -- Walter E. Washington Convention Center, Washington, DC WASHINGTON, Nov. 4, 2013 /PRNewswire/ -- Acetaminophen is the leading cause of acute liver failure in the US. In January 2011, the Federal Drug Administration asked manufacturers to limit the strength of acetaminophen in prescription drug products. They also requested a Boxed Warning for severe liver injury to be added to the label of all prescription drug products that contain acetaminophen. The...

2013-07-10 15:27:35

Efforts to develop a safer form of acetaminophen — the pain and fever-reducer that is one of the most widely used drugs — have led to discovery of substances that may have less potentially toxic effects on the liver. A report on the research appears in ACS Medicinal Chemistry Letters. Roman Shchepin and colleagues explain that a link exists between acetaminophen and liver damage. The damage may be severe and can occur with intentional and accidental...

2013-04-18 21:29:37

A certain number of patients hospitalized for cirrhosis complications soon develop a syndrome characterized by acute liver failure and/or the failure of other vital organs (ACLF). This syndrome had no specific diagnostic criteria hitherto. In this prospective study, led by Dr Richard Moreau, INSERM Research Director (Mixed Research Unit 773 “Centre de Recherche biomédicale Bichat-Beaujon”; INSERM/Université Paris Diderot) who is also a practitioner...

2012-11-14 14:30:31

Early changes in liver function detected by novel techniques can identify severe infection (sepsis) hours after onset and so could have important implications for the treatment of patients who are critically ill, according to a groundbreaking study by European researchers published in this week's PLOS Medicine. Almost half of all people who develop severe sepsis die as this life-threatening condition often develops quickly and is often diagnosed too late to save the patient's life. In...

2012-11-10 08:21:32

BOSTON, Nov. 10, 2012 /PRNewswire/ -- Among patients with acetaminophen-induced acute liver failure (ALF), bariatric surgery was 25 times more common than in the general population. Researchers at California Pacific Medical Center (CPMC) reported an alarming rate of bariatric surgery among patients with ALF from acetaminophen poisoning. They studied 101 patients with ALF between 2009 and 2011, of whom 54 had acetaminophen-induced ALF. Of those 54 patients 9 - or 16.7...

2012-11-08 08:34:56

SAN DIEGO, Nov. 8, 2012 /PRNewswire/ -- Ocera Therapeutics, Inc. announced that the first patient has enrolled in a Phase 2a study to evaluate the safety and tolerability of OCR-002 (ornithine phenylacetate) in the treatment of patients with acute liver injury (ALI) as well as those that have progressed to acute liver failure (ALF) following acetaminophen overdose. OCR-002 is an investigational drug designed to directly reduce circulating blood levels of ammonia which, at high levels, is...