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Latest Adenocarcinoma Stories

2012-04-03 09:10:45

The dietary supplement gamma-linoleic acid can inhibit the growth of a subset of pancreatic cancer cells and selectively promote cancer cell death in mice, a Mayo Clinic study has found. The supplement, a fatty acid also known as GLA, worked particularly well when combined with the chemotherapy drug gemcitabine, the researchers say. The findings were presented today by Mayo Clinic pathologist Ruth Lupu, Ph.D., at the American Association for Cancer Research (AACR) Annual Meeting 2012. "One of...

2012-03-21 00:38:11

New study shows how to defeat chemotherapy barrier in nation's 4th deadliest cancer Scientists at Fred Hutchinson Cancer Research Center and the Translational Genomics Research Institute (TGen) have discovered a literal 'break through' in pancreatic cancer. A unique biological barrier that pancreatic cancer tumors build around themselves have made them especially resistant to chemotherapy treatments, according to the Hutchinson Center/TGen study published today in the highly-regarded...

2012-03-19 16:54:33

Research study reports extending survival in mice by 70 percent; initial studies in humans are under way Pancreas cancer tumors spread quickly and are notoriously resistant to treatment, making them among the deadliest of malignancies. Their resistance to chemotherapy stems in part from a unique biological barrier the tumor builds around itself. Now scientists at Fred Hutchinson Cancer Research Center have found a way to break through that defense, and their research represents a potential...

2012-02-28 11:49:48

UT MD Anderson scientists find molecular path of protein associated with hard-to-treat cancers A protein abundantly found in treatment-resistant cancers holds an important tumor-suppressor out of the cell nucleus, where it would normally detect DNA damage and force defective cells to kill themselves, a team of scientists reports in the current Cancer Cell. "Overexpression of Aurora Kinase-A in tumors has been correlated with resistance to DNA-damaging chemotherapy, but we haven't known...

2012-01-13 06:50:42

(Ivanhoe Newswire) — Until now, researchers have not examined never-smokers as extensively as they have smokers as potential lung cancer patients. Never-Smokers — individuals who smoke fewer than 100 cigarettes in his/her lifetime–are estimated to account for 10 percent of lung cancer cases. Today, researchers have begun to identify which mutations and pathway changes lead to lung cancer in never-smokers, this a first step towards developing potential therapeutic targets....

2012-01-09 19:52:47

Researchers have begun to identify which mutations and pathway changes lead to lung cancer in never-smokers – a first step in developing potential therapeutic targets. Never-smokers (defined as an individual who smoked fewer than 100 cigarettes in his or her lifetime) are estimated to account for 10 percent of lung cancer cases. However, in the past, researchers have not examined this patient population as extensively as they have studied patients with lung cancer who smoked,...

2012-01-09 19:51:39

Multicentric carcinogenesis with the same genetic mutation appears to occur in lung adenocarcinoma, according to data presented at the AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer: Biology, Therapy and Personalized Medicine, held Jan. 8-11, 2012. Data also demonstrated that the EGFR and KRAS genes, which are mutually exclusive, can be used to define clinically relevant molecular subsets of lung adenocarcinoma and can define tumor clonality. "The information on genetic...

2012-01-09 12:19:22

Study presented at AACR-IASLC conference of multiple novel mutations and pathway changes not found in patients with lung cancer who smoked Researchers at the Translational Genomics Research Institute (TGen) have begun to identify mutations and cellular pathway changes that lead to lung cancer in never-smokers – a first step in developing potential therapeutic targets. "This is the starting point. We certainly have a lot of pathways and gene expression alterations that we're going...

2012-01-04 06:22:32

(Ivanhoe Newswire) — Smoking is a well-known risk factor for lung cancer, but about 25% of all lung cancer patients have never smoked. According to this study, a gene fusion event could explain a significant proportion of these lung cancer cases, and may serve as a target for new therapies. Recent strides have been made to identify gene mutation events driving cases of lung adenocarcinoma in never-smokers, but the underlying genetic events leading to these lung cancers still remain...

2011-12-23 00:54:36

Smoking is a well-known risk factor for lung cancer, but nearly 25% of all lung cancer patients have never smoked. In a study published online today in Genome Research (www.genome.org), researchers have identified a previously unknown gene fusion event that could explain a significant proportion of lung cancer cases in never-smokers, and might serve as a target for new therapies. Recent strides have been made to identify gene mutation events driving cases of lung adenocarcinoma in...


Word of the Day
tesla
  • The unit of magnetic flux density in the International System of Units, equal to the magnitude of the magnetic field vector necessary to produce a force of one newton on a charge of one coulomb moving perpendicular to the direction of the magnetic field vector with a velocity of one meter per second. It is equivalent to one weber per square meter.
This word is named for Nikola Tesla, the inventor, engineer, and futurist.