Latest Adenocarcinoma Stories
BOSTON, July 1 /PRNewswire-USNewswire/ -- Cancer stem cells have enticed scientists because of the potential to provide more durable and widespread cancer cures by identifying and targeting the tumor's most voracious cells. Now, researchers at Children's Hospital Boston and their colleagues have identified cancer stem cells in a model of the most common form of human lung cancer and, more significantly, have found that the cancer stem cells may vary from tumor to tumor, depending upon the...
Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant digestive tumor with a very poor prognosis. Hypoxia-inducible transcription factor-1α (HIF-1α) is involved in malignant progression in many solid tumors, including PDAC, upregulation of HIF-1α accelerates PDAC progression, but the exact regulatory mechanisms of HIF-1αin PDAC has not been unequivocally addressed. Recently, an increasing number of studies reported that toll-like receptors (TLRs) were upregulated in...
A 30-year evaluation of the surgical outcomes for non-small cell lung cancerResearch published in the June edition of the Journal of Thoracic Oncology sought to investigate the time trends of surgical outcomes of patients with non-small cell lung cancer (NSCLC) between 1979 and 2008. The incidence of lung cancer continues to rise; therefore, countermeasures to decrease death rates have become an important public health issue. After analyzing the time trends, researchers postulated that the...
Detection and removal may lower cancer riskWorking with researchers from the University of Michigan and Indiana University, Van Andel Research Institute (VARI) investigators have developed a method that could be used to predict whether pancreatic cysts are benign or are precursors to invasive cancer. More pancreatic cysts are being detected due to the widespread use of high resolution abdominal imaging. These advances in early detection, when coupled with the new findings, could result in...
In the largest study to date of a rare and deadly form of bladder cancer, researchers at Henry Ford Hospital in Detroit found radiation therapy may not improve a patient's chances for survival.While overall survival for adenocarcinoma of the bladder was poor, the study revealed several factors that may improve a patient's prognosis, including being diagnosed at age 60 or younger, and having cystectomy, a procedure that either removes all or a portion of the bladder."While this malignancy...
Cancer of the pancreas"“"“a glandular organ that lies behind the stomach and secretes vital enzymes and hormones"“"“seldom is detected in early stages, making treatment difficult and survival statistics particularly grim. However, new research from Fox Chase Cancer Center finds that patients with pancreatic adenocarcinoma whose tumors respond most to preoperative chemotherapy and radiation survive four times as long, on average, as those whose tumors respond least.The research, led by...
AMES, Iowa, May 27 /PRNewswire/ -- NewLink Genetics Corporation announced today treatment of the first patient in a nationwide Phase 3 clinical trial of its HyperAcute®-Pancreas cancer immunotherapy for patients who have successfully undergone pancreatic surgical resection. "This pivotal study represents one of the largest Phase 3 clinical trials of immunotherapy ever conducted for pancreatic cancer in the United States," said Charles Link, M.D., chairman and chief executive officer of...
CALGARY, AB, May 18 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. ("Oncolytics") (TSX:ONC, NASDAQ:ONCY) announced today that a paper entitled "Two-Stage Phase I Dose-Escalation Study of Intratumoural Reovirus Type 3 Dearing and Palliative Radiotherapy in Patients with Advanced Cancers," has been published in the online version of the journal Clinical Cancer Research. The paper covers final results from a Phase Ia/Ib U.K. clinical trial (REO 006) investigating the intratumoural delivery...
Poor diet, too much alcohol, smoking and increasing obesity could be leading to an epidemic of esophageal and upper stomach cancer, according to a leading UK team of specialists at The University of Nottingham and Nottingham University Hospitals.The Nottingham Gastro-Esophageal Cancer Research Group has been carrying out intensive research over the past five years to try to improve the treatment of this cancer. A major part of the research is published today in the British Journal of Cancer....
INDIANAPOLIS, April 1 /PRNewswire-FirstCall/ -- Eli Lilly and Company (NYSE: LLY) announced today that its chemotherapy ALIMTA® (pemetrexed for injection) received a positive "Final Appraisal Determination" from the United Kingdom's National Institute for Health and Clinical Excellence (NICE). Specifically, NICE's Final Appraisal Determination recommends ALIMTA as an option for the maintenance treatment of people with locally advanced or metastatic non-small cell lung cancer with other...
