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Latest adenosine Stories

2009-06-03 08:00:00

Adenosine Regulation with GP531 Improves the Heart's Pumping Function in Dogs with Advanced Chronic Heart Failure NEW YORK, June 3 /PRNewswire/ -- PeriCor Therapeutics, Inc. announced today that positive preclinical results of its novel cardioprotective agent, GP531, were reported in a poster presentation by Hani N. Sabbah, Ph.D., at the European Heart Failure Congress 2009 in Nice, France. The study was funded by PeriCor Therapeutics, Inc. and conducted by Dr. Sabbah and colleagues at the...

2009-06-02 07:15:00

LA JOLLA, Calif., June 2 /PRNewswire-FirstCall/ -- Cordex Pharma, Inc. (OTC Bulletin Board: CDXP) announced today that the U.S. Food and Drug Administration (FDA) has approved the design of pivotal, Phase 2b/3 clinical trials evaluating its lead product ATPace(TM) as an antiarrhytmic drug for the acute treatment of patients with paroxysmal supraventricular tachycardia (PSVT) under the Special Protocol Assessment (SPA) process. ATPace(TM) is a novel stable liquid formulation of adenosine...

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2009-04-08 14:38:34

A small study suggests that a couple cups of coffee before a tough workout may lower the chances of sore muscles later on, Reuters reported. Young men who performed an intense bout of cycling reported less muscle soreness after a pre-workout dose of caffeine, researchers said. The study, reported in the International Journal of Sports Nutrition and Exercise Metabolism, said the benefits were seen in both habitual caffeine consumers and those who typically avoided caffeine. Previous studies...

2009-04-08 11:08:36

New report in the FASEB Journal lays the blueprint for new constipation drugs If you hate prune juice and chalky fiber supplements, just sit down and relax. Help is on the way. In a research report published online in The FASEB Journal, a team of researchers has discovered a new way to make it a lot easier to go to the bathroom, especially when all other methods fail. Specifically, they have found a group of nerve ending receptors which, when stimulated, causes the bowels to pass waste, and...

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2009-03-31 08:38:36

A little java makes it easier to jive, researcher says Stopping to smell the coffee "“ and enjoy a cup of it "“ before your morning workout might do more than just get your juices flowing. It might keep you going for reasons you haven't even considered. As a former competitive cyclist, University of Illinois kinesiology and community health professor Robert Motl routinely met his teammates at a coffee shop to fuel up on caffeine prior to hitting the pavement on long-distance...

2009-03-04 11:38:00

LA JOLLA, Calif., March 4 /PRNewswire-FirstCall/ -- Cordex Pharma, Inc. (OTC Bulletin Board: CDXP) announced today that it has filed a formulation patent covering its lead product, ATPace. ATPace is a stable liquid formulation of adenosine triposphate (ATP) for intravenous administration. ATPace is being developed as a therapeutic drug for the acute management of paroxysmal supraventricular tachycardia (PSVT) as well as a diagnostic test for the identification of patients with bradycardic...

2009-02-23 07:30:00

Phase 3 clinical oversight and regulatory services for Cordex's ATPace arrhythmia drug to be provided by Cato Research LA JOLLA, Calif., Feb. 23 /PRNewswire-FirstCall/ -- Cordex Pharma, Inc. (OTC Bulletin Board: CDXP) announced today that it has entered into a long-term strategic master services equity agreement with Cato BioVentures. As part of this agreement, Cato BioVentures will, at the request of Cordex, arrange for Cato Research to perform regulatory services and oversight of...

2009-02-18 07:30:00

LA JOLLA, Calif., Feb. 18 /PRNewswire-FirstCall/ -- Cordex Pharma, Inc. (OTC Bulletin Board: CDXP) announced today that it has submitted to the U.S. Food and Drug Administration (FDA) an amended Phase 3 protocol for ATPace to be reviewed as a Special Protocol Assessment (SPA). The amendment addresses written comments recently received from the FDA in response to the Company's initial SPA submission to the FDA on November 20, 2008. To address the FDA's main comments, Cordex has changed the...

2009-01-29 09:36:08

Brain cells called astrocytes help to cause the urge to sleep that comes with prolonged wakefulness, according to a study in mice, funded by the National Institutes of Health. The cells release adenosine, a chemical known to have sleep-inducing effects that are inhibited by caffeine."Millions of Americans suffer from disorders that prevent a full night's sleep, and others "“ from pilots to combat soldiers "“ have jobs where sleepiness is a hazard. This research could lead to...

2009-01-29 08:22:52

Scientists have discovered an unexpected brain mechanism that modulates the regulation of sleep and the consequences of sleep deprivation. The research, published by Cell Press in the January 29th issue of the journal Neuron, opens new avenues for development of treatments for disorders and cognitive deficits associated with sleep loss.Glial cells are brain cells that do not transmit nerve impulses the way that neurons do. Astrocytes are a type of glial cell that play multiple supportive...